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Table 4 Comparison of the mean FACT-G, FLIC and EORTC QLQ-C30 total/global functioning scores by ECOG score and presentation order(a)

From: Order effects: a randomised study of three major cancer-specific quality of life instruments

Order ECOG score FACT-G FLIC EORTC QLQ-C30
A 0–1 83.93 119.37 58.73
  2–4 74.54 110.11 52.18
Difference in means 9.39 (p < 0.001) 9.26 (p = 0.002) 6.55 (p = 0.014)
B 0–1 80.64 118.39 64.21
  2–4 73.96 110.13 54.06
Difference in means 6.69 (p = 0.001) 8.26 (p = 0.004) 10.15 (p < 0.001)
Difference in A – difference in B 2.70 1.00 -3.60
90% CI (-1.83 to 7.24) (-5.88 to 7.88) (-9.70 to 2.50)
  1. (a) Order A and order B mean, respectively, the HRQoL instrument was placed first and second in the questionnaire.