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Table 4 Hierarchical multiple linear analyses of the influence of initial CD4 value and the variables viral response, subjective experience of adverse effects and adherence on the change in PCS and ECS from before start (pre PI-ART) to after two year of treatment (follow-up)

From: The two-year impact of first generation protease inhibitor based antiretroviral therapy (PI-ART) on health-related quality of life

  Follow-up PCS Follow-up ECS
Step 1 Partial correlation a   Partial correlation a  
Pre PI-ART PCS 0.722***   -  
Pre PI-ART ECS -   0.681***  
R2 0.605***   0.456***  
F 78.26   42.72  
d.f. (regression;residual) 1;51   1;51  
Step 2 Partial correlation   Partial correlation  
Viral response 0.202   0.076  
Adherence 0.167   0.235  
Adverse effects 0.091   -0.366*  
Pre PI-ART CD4 value -0.043   -0.024  
R2-change 0.028   0.128*  
F-change 0.91   3.63  
d.f. (regression;residual) 4;47   4;47  
  1. PCSPhysical HRQL composite score; ECSEmotional HRQL composite score; PI-ARTProtease inhibitor based antiretroviral therapy; apartial correlation of the final model (step 2); *p < 0.05; ***p < 0.001