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Table 4 Hierarchical multiple linear analyses of the influence of initial CD4 value and the variables viral response, subjective experience of adverse effects and adherence on the change in PCS and ECS from before start (pre PI-ART) to after two year of treatment (follow-up)

From: The two-year impact of first generation protease inhibitor based antiretroviral therapy (PI-ART) on health-related quality of life

 

Follow-up PCS

Follow-up ECS

Step 1

Partial correlation a

 

Partial correlation a

 

Pre PI-ART PCS

0.722***

 

-

 

Pre PI-ART ECS

-

 

0.681***

 

R2

0.605***

 

0.456***

 

F

78.26

 

42.72

 

d.f. (regression;residual)

1;51

 

1;51

 

Step 2

Partial correlation

 

Partial correlation

 

Viral response

0.202

 

0.076

 

Adherence

0.167

 

0.235

 

Adverse effects

0.091

 

-0.366*

 

Pre PI-ART CD4 value

-0.043

 

-0.024

 

R2-change

0.028

 

0.128*

 

F-change

0.91

 

3.63

 

d.f. (regression;residual)

4;47

 

4;47

 
  1. PCSPhysical HRQL composite score; ECSEmotional HRQL composite score; PI-ARTProtease inhibitor based antiretroviral therapy; apartial correlation of the final model (step 2); *p < 0.05; ***p < 0.001