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Table 4 Adult pertussis – days or years traded, utilities and willingness-to-pay to avoid health states

From: Health-state valuations for pertussis: methods for valuing short-term health states

 

Vaccination health states

Disease health states

 

Local reaction

Systemic reaction

Mild cough

Severe cough

Pneumonia

Short-term TTO (N = 72)

     

Days traded

     

   Mean (SD)

24 (135)

26 (130)

80 (366)

99 (446)

101 (448)

   Median [25%–75%]

0 [0–2]

2.5 [0–7]

8.5 [0.5–28]

14 [2–56]

14 [2–49]

Utilities*

     

   Mean (SD)

0.95 (0.18)

0.93 (0.18)

0.85 (0.26)

0.81 (0.30)

0.82 (0.30)

   Median [25%–75%]

1.0 [0.99–1.0]

0.99 [0.95–1.0]

0.96 [0.88–1.0]

0.95 [0.81–0.99]

0.96 [0.83–0.99]

Long-term TTO (N = 56)

     

Years traded

     

   Mean (SD)

0.4 (0.8)

1.4 (2.2)

2.7 (3.4)

4.7 (6.3)

4.7 (6.2)

   Median [25%–75%]

0.03 [0–0.9]

0.8 [0.04–1.5]

1 [0.6–4.5]

2 [1–5]

2 [0.8–5]

Utilities*

     

   Mean (SD)

0.995 (0.01)

0.98 (0.03)

0.96 (0.06)

0.92 (0.14)

0.92 (0.16)

   Median [25%–75%]

1.0 [0.99–1.0]

0.99 [0.98–1.0]

0.99 [0.96–1.0]

0.97 [0.92–0.99]

0.97 [0.91–0.99]

Willingness-to-pay (N = 126)

     

   Mean (SD)

$8 (17)

$41 (78)

$3,249 (14,062)

$4,141 (15,409)

$8,748 (66,907)

   Median [25%–75%]

$3 [0–9]

$13 [6–38]

$450 [150–1,200]

$750 [300–1,500]

$750 [300–1,500]

  1. *Utilities were calculated assuming the maximum amount of time traded could not exceed the duration of the health state in the adult and assuming a discount rate of 3%.