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Table 6 Comparison of robust and bootstrap SE's and CI's from the EARLY RA data with a Marginal Model and exchangeable autocorrelation

From: The use of bootstrap methods for analysing health-related quality of life outcomes (particularly the SF-36)

Dependent   Coefficients 95% CI Interval
Variable   SE /SE p Lower Upper Length Shape
Physical Function (n = 222) time 0.11 0.03 3.63 0.001 0.05 0.18 0.12 1.00
    0.03 3.72   0.05 0.18 0.12 0.97
  group 2.82 2.25 1.25 0.211 -1.60 7.24 8.84 1.00
    1.72 1.64   -0.51 6.13 6.64 0.99
Role Physical (n = 221) time -0.06 0.07 -0.90 0.366 -0.19 0.07 0.26 1.00
    0.07 -0.94   -0.19 0.06 0.25 0.91
  group 9.49 3.93 2.42 0.016 1.79 17.19 15.40 1.00
    3.22 2.95   3.63 16.62 12.99 1.22
Bodily Pain (n = 222) time 0.16 0.03 4.69 0.001 0.10 0.23 0.14 1.00
    0.03 4.88   0.10 0.23 0.13 1.05
  group 4.23 1.97 2.14 0.032 0.36 8.10 7.74 1.00
    1.50 2.82   1.44 7.25 5.81 1.08
General Health (n = 221) time 0.04 0.03 1.67 0.095 -0.01 0.09 0.10 1.00
    0.03 1.68   -0.01 0.09 0.10 0.95
  group -4.61 1.96 -2.35 0.019 -8.46 -0.76 7.69 1.00
    1.51 -3.04   -7.36 -1.28 6.07 1.21
Vitality (n = 220) time 0.09 0.03 3.09 0.002 0.03 0.14 0.11 1.00
    0.03 3.05   0.04 0.15 0.11 1.24
  group 2.67 1.80 1.48 0.14 -0.87 6.20 7.07 1.00
    1.41 1.89   -0.19 5.42 5.61 0.96
Social Function (n = 222) time 0.03 0.03 0.77 0.442 -0.04 0.09 0.13 1.00
    0.03 0.79   -0.04 0.09 0.13 0.97
  group 2.40 2.11 1.14 0.255 -1.73 6.54 8.27 1.00
    1.65 1.46   -0.72 5.88 6.61 1.11
Role Emotional (n = 221) time -0.02 0.07 -0.32 0.752 -0.17 0.12 0.29 1.00
    0.08 -0.31   -0.18 0.12 0.30 0.93
  group 4.14 3.91 1.06 0.29 -3.52 11.81 15.33 1.00
    2.93 1.41   -1.54 10.11 11.64 1.05
Mental Health (n = 221) time 0.02 0.03 0.69 0.489 -0.03 0.07 0.10 1.00
    0.03 0.68   -0.03 0.07 0.10 1.15
  group 1.53 1.67 0.92 0.359 -1.74 4.79 6.53 1.00
    1.34 1.14   -0.93 4.42 5.35 1.18
  1. Note: The bootstrap estimates of SE and BC a Confidence Intervals are shown in italics below the model based estimates and are based on 1000 resamples.