All patients | Available QoL | Missing QoL | All patients | |||||
---|---|---|---|---|---|---|---|---|
Variable | Class | N | % | N | % | N | % | P |
Age | ≤65 | 353 | 57 | 138 | 55 | 215 | 58 | |
>65 | 267 | 43 | 111 | 45 | 156 | 42 | 0.2900 | |
Gender | Male | 367 | 59 | 151 | 61 | 216 | 58 | |
Female | 252 | 41 | 98 | 39 | 154 | 42 | 0.5739 | |
PS | 0 | 333 | 54 | 122 | 49 | 211 | 57 | |
1 | 239 | 38 | 110 | 44 | 129 | 35 | ||
2 | 48 | 8 | 17 | 7 | 31 | 8 | 0.0611 | |
Number of sites | 1 | 354 | 58 | 147 | 59 | 207 | 57 | |
>1 | 260 | 42 | 102 | 41 | 158 | 43 | 0.5672 | |
Liver involvement | No | 149 | 24 | 52 | 21 | 97 | 27 | |
Yes | 460 | 76 | 197 | 79 | 263 | 73 | 0.0872 | |
Metastases | Synchronous | 415 | 68 | 168 | 68 | 247 | 68 | |
Metachronous | 196 | 32 | 80 | 32 | 116 | 32 | 0.9374 | |
Adjuvant chemotherapy | No | 488 | 79 | 200 | 81 | 288 | 78 | |
Yes | 130 | 21 | 48 | 19 | 82 | 22 | 0.4013 | |
Tumour site | Colon | 398 | 64 | 160 | 64 | 238 | 64 | |
Rectum | 211 | 34 | 86 | 35 | 125 | 35 | ||
both | 11 | 2 | 3 | 1 | 8 | 1 | 0.6730 | |
LDH | ≤1xULN | 380 | 61 | 134 | 56 | 246 | 66 | |
>1xULN | 240 | 39 | 115 | 44 | 125 | 34 | 0.0017 | |
ALP | ≤1xULN | 350 | 56 | 129 | 52 | 221 | 60 | |
>1xULN | 270 | 44 | 120 | 48 | 150 | 40 | 0.0560 | |
CEA | ≤1xULN | 177 | 28 | 61 | 25 | 116 | 31 | |
>1xULN | 443 | 72 | 188 | 75 | 255 | 69 | 0.0673 | |
EuroQoL | ||||||||
Mobility | 1 | 223 | 81 | 223 | 81 | |||
2-3 | 54 | 19 | 54 | 19 | ||||
Self-care | 1 | 255 | 93 | 255 | 93 | |||
2-3 | 19 | 7 | 19 | 7 | ||||
Usual activities | 1 | 193 | 71 | 193 | 71 | |||
2-3 | 79 | 29 | 79 | 29 | ||||
Pain/discomfort | 1 | 137 | 50 | 137 | 50 | |||
2-3 | 138 | 50 | 138 | 50 | ||||
Anxiety/depression | 1 | 145 | 53 | 145 | 53 | |||
2-3 | 130 | 47 | 130 | 47 | ||||
VAS score | 70 [10–100] ** |