Figure 3

Survival strata according to the Köhne prognostic model before and after improvement. A: Overall survival (in months) for good, intermediate and poor prognosis according to the Köhne prognostic model. Median survival = 20.7 [17.7 – 24.4] for the group with good prognosis (n = 134); Median survival = 18.6 [17.1 – 25.4] for the group with intermediate prognosis (n = 84); Median survival = 9.0 [7.3 -14.7] for the group with poor prognosis (n = 18). Log-rank p = 0.0013. Optimism corrected C-index = 0.54. B: Overall survival (in months) for good, intermediate and poor prognosis according to the modified Köhne group. Median survival = 27.0 [21.1 – 37.5] for the group with good prognosis (n = 57); Median survival = 18.4 [16.5 – 21.6] for the group with intermediate prognosis (n = 146); Median survival = 11.3 [9.0 – 16.9] for the group with poor prognosis (n = 33). Log-rank p<0.0001. Optimism corrected C-index = 0.60.