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Table 2 MCID estimates for EQ-5D based on PDDS subgroups

From: Estimating a minimal clinically important difference for the EuroQol 5-dimension health status index in persons with multiple sclerosis

EQ-5D scores

PDDS*

N

Mean

SD

Median

Min

Max

SEM

0.5 SD

0.33 SD

0

526

0.900

0.119

1.000

0.26

1.00

0.066

0.060

0.040

1

428

0.834

0.117

0.827

0.37

1.00

0.065

0.059

0.039

2

241

0.734

0.147

0.778

0.29

1.00

0.082

0.074

0.049

3

429

0.730

0.163

0.778

0.20

1.00

0.091

0.081

0.054

4

507

0.689

0.167

0.761

0.17

1.00

0.093

0.084

0.056

5

427

0.662

0.171

0.708

0.05

1.00

0.095

0.086

0.057

6

399

0.649

0.177

0.705

0.05

1.00

0.099

0.089

0.059

7

83

0.616

0.182

0.689

-0.04

0.85

0.101

0.091

0.061

8

4

0.463

0.284

0.410

0.18

0.85

0.158

0.142

0.095

Mean Weighted MCID

3044

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0.084

0.076

0.051

  1. N = number of patients; PDDS = Patient Determined Disease Steps; SEM = standard error of the measurement; SD = standard deviation.
  2. *PDDS Score 0 = mild to no symptoms; 1 = mild disability; 2 = moderate disability; 3 = gait disability; 4 = early cane; 5 = late cane; 6 = bilateral support; 7 = wheel chair/scooter; 8 = bedridden.
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Health and Quality of Life Outcomes

ISSN: 1477-7525

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