Median Change in EQ-5D Health Utility Score From Baseline for Seattle Angina Questionnaire Angina Frequency Domain Score Class Responders and Non-Responders. This figure presents box-and-whisker plots for the change in EQ-5D health utility score from baseline for SAQAF class responders (improving by at least one classification) and non-responders based upon data from both mapping equations. For each plot, the central box spans the first quartile to the third quartile (or the interquartile range), with the black line dividing the box depicting the median value for the subjects. The whiskers above and below the box show the minimum and maximum subject values. *Mapping Equation 1 = Wijeysundera 2011 . ±Mapping Equation 2 = Goldsmith 2010 . †p-values calculated using Mann–Whitney U tests.