| Categories of change in physician global assessment of disease activity | ||||||
---|---|---|---|---|---|---|---|
 | > +10 (n = 8) | +10 to -10 (n = 44) | -11 to -20 (n = 33) | -21 to -40 (n = 56) | < -40 (n = 43) | F | p-value |
PRO Instruments | Â | Â | Â | Â | Â | Â | Â |
SF-36 | Â | Â | Â | Â | Â | Â | Â |
Physical functioning | -5.6 (27.9) | 1.6 (13.2) | 2.7 (12.6) | 10.1 (19.5) | 14.3 (19.7) | 4.8 | 0.0010 |
Role physical | -8.9 (13.0) | 1.8 (17.7) | 6.3 (19.4) | 11.2 (21.2) | 21.0 (25.9) | 6.4 | 0.0001 |
Bodily pain | -6.6 (13.4) | -0.8 (15.7) | 6.4 (18.8) | 14.3 (14.2) | 22.2 (22.3) | 12.3 | 0.0000 |
General health | -5.9 (17.2) | -1.2 (14.7) | 4.2 (12.4) | 3.6 (14.6) | 8.5 (13.3) | 3.4 | 0.0097 |
Vitality | 0.0 (13.8) | -3.1 (18.5) | 1.9 (19.7) | 7.4 (13.8) | 20.7 (22.1) | 10.3 | 0.0000 |
Social functioning | -15.6 (23.8) | -3.1 (24.1) | 0.0 (22.9) | 8.7 (19.9) | 16.7 (30.9) | 5.7 | 0.0003 |
Role emotional | -10.4 (25.5) | -3.4 (23.7) | 1.9 (22.9) | 7.7 (24.6) | 13.3 (28.9) | 3.4 | 0.0109 |
Mental health | -8.1 (13.1) | -4.0 (15.4) | 5.0 (16.2) | 4.0 (16.7) | 14.5 (19.7) | 7.6 | 0.0000 |
Physical summary | -1.8 (8.0) | 1.0 (4.9) | 1.9 (4.9) | 4.5 (5.9) | 6.5 (7.8) | 6.7 | 0.0000 |
Mental summary | -4.8 (10.5) | -.27 (9.2) | 1.1 (8.9) | 2.4 (8.6) | 7.5 (12.8) | 6.5 | 0.0001 |
HAQ-DI | 0.03 (0.44) | 0.05 (0.33) | -0.14 (0.36) | -0.28 (0.41) | -0.54 (0.53) | 9.1 | 0.0000 |
FACIT-Fatigue | -4.7 (5.5) | -0.6 (7.8) | 2.5 (7.1) | 4.1 (6.2) | 9.6 (7.2) | 14.8 | 0.0000 |