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Table 1 Demographics, clinical characteristics, and baseline HRQoL scores of participants randomized to four secukinumab dose groups (N = 187)

From: Secukinumab treatment in rheumatoid arthritis is associated with incremental benefit in the clinical outcomes and HRQoL improvements that exceed minimally important thresholds

Demographics

 

Female (n, %)

149 (79.7)

Age (mean, SD)

54.9 (10.8)

Caucasian (n, %)

137 (73.3)

Clinical assessment

 

Prior use of biologics (n, %)

38 (20.3)

VAS pain intensity (mean, SD)

53.6 (20.8)

SDAI (mean, SD)

40.3 (11.9)

Patient global assessment disease activity (mean, SD)

61.6 (19.1)

Physician global assessment disease activity (mean, SD)

61.9 (14.9)

Swollen joint count (mean, SD)

11.4 (4.8)

Tender joint count (mean, SD)

14.7 (6.2)

HRQoL scales

 

SF-36 Physical functioning (mean, SD)

40.5 (21.7)

SF-36 Role physical (mean, SD)

42.8 (24.3)

SF-36 Bodily pain (mean, SD)

36.1 (16.9)

SF-36 General health (mean, SD)

40.4 (16.6)

SF-36 Vitality (mean, SD)

39.0 (19.7)

SF-36 Social functioning (mean, SD)

57.2 (26.1)

SF-36 Role emotional (mean, SD)

54.1 (26.7)

SF-36 Mental health (mean, SD)

56.8 (19.4)

SF-36 Physical summary (mean, SD)

33.8 (7.5)

SF-36 Mental summary (mean, SD)

40.5 (11.0)

HAQ-DI (mean, SD)

1.49 (0.6)

FACIT-Fatigue (mean, SD)

28.3 (10.1)