Table 7 Factors associated with HRQL and with SWB and parameters estimates of MANCOVA analysis for subgroups of disease

QoL - General Well-being

Dispositional Optimism

5.44

6.54

2.48

0.56 (0.24)

0.68 (0.27)

0.56 (0.35)

2.31

2.56

1.58

0.021

0.011

0.117

Positive Affect

26.19

9.83

7.53

6.14 (1.20)

4.19 (1.34)

4.51 (1.64)

5.12

3.14

2.74

<0.001

0.02

0.007

Negative Affect

28.67

40.02

13.52

−6.09 (1.14)

−9.71 (1.54)

−6.96 (1.89)

−5.36

−6.33

−3.86

<0.001

<0.001

<0.001

Spirituality

3.79

0.03

4.13

2.29 (1.18)

0.25 (1.43)

3.29 (1.62)

1.95

0.18

2.03

0.052

0.862

0.044

Social Support

2.82

0.02

0.18

0.07 (0.04)

−0.01 (0.05)

0.02 (0.05)

1.68

−0.15

0.42

0.094

0.879

0.673

Treatment Adherence

2.28

1.56

1.36

2.12 (1.40)

2.76 (2.21)

3.08 (2.64)

1.51

1.25

1.17

0.132

0.213

0.244

QoL - Physical Health

Dispositional Optimism

0.39

1.52

0.75

−0.02 (0.04)

−0.06 (0.05)

−0.07 (0.09)

−0.63

1.23

−0.87

0.529

0.219

0.387

Positive Affect

4.47

0.92

2.60

−0.38 (0.18)

−0.02 (0.23)

−0.64 (0.39)

−2.11

−0.96

−1.61

0.035

0.339

0.015

Negative Affect

12.28

20.17

<0.001

0.60 (0.17)

1.19 (0.26)

<0.001 (0.46)

3.50

4.49

<0.001

0.001

<0.001

1.000

Spirituality

0.22

1.23

1.09

0.08 (0.17)

0.27 (0.25)

0.40 (0.39)

0.46

1.11

1.04

0.643

0.269

0.298

Social Support

5.25

1.83

11.86

−0.01 (0.01)

0.11 (0.01)

−0.04 (0.01)

−2.29

1.35

−3.44

0.023

0.178

0.001

Treatment Adherence

9.91

4.57

0.81

−0.67 (0.21)

−0.82 (0.38)

−0.57 (0.64)

−3.15

−2.14

−0.89

0.002

0.034

0.371

QoL - Mental Health

Dispositional Optimism

1.21

2.40

1.85

−0.03 (0.03)

−0.06 (0.04)

−0.07 (0.05)

−1.10

−1.55

−1.34

0.272

0.123

0.176

Positive Affect

10.31

7.90

3.33

−0.46 (0.14)

−0.05 (0.19)

−0.04 (0.22)

−3.21

−2.81

−1.82

0.001

0.006

0.007

Negative Affect

99.35

52.97

37.85

1.36 (0.14)

1.55 (0.21)

1.55 (0.25)

9.97

7.28

6.15

<0.001

<0.001

<0.001

Spirituality

0.36

0.01

3.96

−0.09 (0.14)

−0.02 (0.19)

−0.43 (0.22)

−0.60

−0.11

−1.99

0.549

0.911

0.048

Social Support

5.10

1.72

2.22

−0.01 (0.01)

0.01 (0.01)

−0.01 (0.01)

−2.26

−1.31

−1.49

0.025

0.192

0.138

Treatment Adherence

2.09

3.18

0.50

−0.24 (0.17)

−0.55 (0.31)

−0.25 (0.35)

−1.45

−1.78

−0.71

0.149

0.076

0.481

Subjective Well-being

Dispositional Optimism

2.38

1.29

0.95

0.37 (0.24)

0.34 (0.29)

0.32 (0.32)

1.54

1.13

0.98

0.121

0.258

0.330

Positive Affect

4.01

3.17

15.75

2.39 (1.19)

2.67 (1.50)

5.89 (1.48)

2.00

1.78

3.97

0.046

0.077

<0.001

Negative Affect

24.09

12.03

8.87

−5.54 (1.13)

−5.97 (1.72)

−5.08 (1.71)

−4.91

−3.47

−2.98

<0.001

0.001

0.003

Spirituality

21.08

9.40

25.98

5.37 (1.17)

4.92 (1.60)

7.46 (1.46)

4.59

3.07

5.09

<0.001

0.003

<0.001

Social Support

28.84

0.25

0.16

0.23 (0.04)

0.03 (0.05)

0.02 (0.05)

5.37

0.49

0.40

<0.001

0.621

0.688

Treatment Adherence

0.56

1.18

0.52

1.04 (1.39)

2.69 (2.49)

1.71 (2.38)

0.75

1.09

0.72

0.456

0.279

0.473