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Table 4 Multi-variable linear stepwise regression on HRQoL scores in chronic hepatitis B patients *

From: Significant impairment of health-related quality of life in mainland Chinese patients with chronic hepatitis B: a cross-sectional survey with pair-matched healthy controls

Dependent variable Independent variable entered in the model Unstandardized coefficient (95% CI) Standardized coefficient P value
SF-36v2 (PCS) Stage of illness -2.548 (-3.795, -1.302) -0.212 0.000
Total bilirubin -0.060 (-0.096, -0.024) -0.171 0.001
Education attainment 1.901 (0.687, 3.116) 0.149 0.002
Duration of illness -0.110 (-0.213, -0.008) -0.102 0.035
SF-36v2 (MCS) Currently taken anti-viral treatment -3.895 (-6.147, -1.644) -0.174 0.001
Education attainment 2.180 (0.247, 4.112) 0.113 0.027
Duration of illness -0.170 (-0.335, -0.006) -0.104 0.043
SF-6D Currently taken anti-viral treatment -0.041 (-0.066, -0.016) -0.164 0.001
Education attainment 0.025 (0.003, 0.048) 0.117 0.029
Total bilirubin -0.001 (-0.001, 0.000) -0.107 0.036
Age -0.001 (-0.002, 0.000) -0.095 0.076
CLDQ (Overall) Age -0.013 (-0.020, -0.006) -0.182 0.000
Annual per capita household income 0.138 (0.038, 0.238) 0.138 0.007
Duration of illness -0.017 (-0.030, -0.003) -0.131 0.013
Currently taken anti-viral treatment -0.203 (-0.375, -0.030) -0.116 0.022
  1. *Only 375 patients with liver function tests are included in the analyses. PCS, physical component summary; MCS, mental component summary. Independent variables include stage of illness (chronic hepatitis B = 1, compensated cirrhosis = 2, decompensated cirrhosis = 3); sex (male = 1, female = 2); occupation (dummy variable); education attainment (no schooling and primary = 1, secondary = 2, tertiary = 3); marital status (married = 1, other marital status = 2); annual per capita household income (<5000 = 1, 5000–9999 = 2, ≥10000 = 3); currently taken anti-viral treatment (no = 1, yes = 2); and other quantitative variables (age, duration of illness, alanine aminotransferase, total bilirubin, and albumin). A variable is entered into the model if the significance level of its F value is less than 0.05 and is removed if greater than 0.1.