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Table 2 Sociodemographic, clinical, functional and psychological characteristics of COPD patients with and without ED visits or hospitalizations in the first and the second year of follow-up

From: Utility of brief questionnaires of health-related quality of life (Airways Questionnaire 20 and Clinical COPD Questionnaire) to predict exacerbations in patients with asthma and COPD

 

1st year

2nd year

ED visits

Hospitalizations

ED visits

Hospitalizations

0

≥1

0

≥1

0

≥1

0

≥1

n = 79

n = 21

n = 87

n = 13

n = 79

n = 21

n = 81

n = 19

Sociodemographic variables

        

Age, year

66.0 ± 7.9

65.5 ± 10.2

65.3 ± 8.7

70.1 ± 5.0

65.2 ± 8.8

68.7 ± 6.1

65.3 ± 8.6

69.0 ± 6.8

Female, n (%)

5 (6)

2 (9)

7 (8)

0 (0)

6 (7)

1 (5)

6 (7)

1 (5)

Age at diagnosis, year

56.8 ± 9.1

55.4 ± 7.5

56.7 ± 8.8

55.8 ± 8.3

56.1 ± 8.7

58.5 ± 9.0

56.3 ± 8.8

57.7 ± 8.7

Disease duration, year

9.1 ± 7.3

9.6 ± 7.7

8.4 ± 6.8

14.3 ± 8.8*

9.0 ± 6.9

10.1 ± 8.8

8.8 ± 7.0

10.8 ± 8.5

Active smoking, n (%)

15(19)

8 (38)**

20(23)

3(23)

19(24)

4(19)

17 (22)

5 (26)

Mean pack-year

63.0 ± 25.1

59.6 ± 27.3

62.9 ± 25.1

58.1 ± 28.3

63.2 ± 2.2

59.1 + 27.0

61.1 ± 24.6

67.4 ± 29.2

Education level, n (%)

        

Illiterate/Primary School

52 (66)

16 (76)

57 (66)

11 (85)

52 (66)

16 (76)

52 (64)

16 (84)

Secondary School/University

27 (34)

5 (24)

30 (34)

2 (15)

27 (34)

5 (24)

29 (36)

3 (16)

Socioeconomic level, n (%)

        

Low/Medium-low

31 (39)

13 (62) **

36 (41)

8 (61)**

34 (43)

10 (48)

34 (42)

10 (53)

Medium-medium/Medium-high/High

48 (61)

8 (38)

51 (59)

5 (39)

45 (57)

11 (52)

47 (58)

9 (47)

Employment status, n (%)

        

Working

11 (14)

4 (19)

15 (17)

0 (0)

14 (18)

1 (5)

15 (18)

0

Retired/Disability

68 (86)

17 (81)

72 (83)

13 (100)

65 (82)

20 (95)

66 (81)

19 (100)*

Place of residence, n (%)

        

Rural

21 (27)

5 (24)

24 (28)

2 (15)

23 (29)

3 (14)

21 (26)

5 (26)

Urban

58 (73)

16 (76)

63 (72)

11 (85)

56 (71)

18 (86)

60 (74)

14 (74)

Marital status n (%)

        

Married/unmarried partner

65 (82)

18 (86)

73 (84)

10 (77)

66 (83)

17 (81)

67 (83)

16 (84)

Single/separated/divorced/widowed

14 (18)

3 (14)

14 (16)

3 (23)

13 (16)

4 (19)

14 (17)

3 (16)

Clinical-functional variables

        

BMI, kg/m2

28.4 ± 4.6

26.0 ± 4.1**

28.2 ± 4.5

25.4 ± 4.4**

28.3 ± 4.6

26.1 ± 4.3

28.1 ± 4.6

26.7 ± 4.7

MRC dyspnea scale, n (%)

        

Grade 0-1-2

68 (86)

15 (72)

74 (85)

12 (92)

66 (84)

17 (81)

69 (85)

14 (74)

Grade 3-4

11 (14)

6(28)

13 (15)

1 (8)

13 (16)

4 (19)

12 (15)

5 (26)

Spirometry

        

FVC post (%)

92.9 ± 2.0

89.5 ± 21.2

92.0 ± 21.5

93.4 ± 25.8

91.6 ± 21.2

94.7 ± 25.2

93.7 ± 22.5

85.7 ± 18.2

FEV1 post (%)

59.5 ± 19.3

57.5 ± 20.5

59.9 ± 18.8

54.0 ± 23.6

59.3 ± 18.3

58.2 ± 24.3

60.8 ± 19.6

51.7 ± 17.6

6MWT, m

394.2 ± 86.5

341.1 ± 120.7**

395.1 ± 83.6

302.3 ± 136.3

393.1 ± 88.4

345.1 ± 117.0

396.8 ± 83.8

324.1 ± 124.3

BODE index (0–10)

1.9 ± 1.9

2.8 ± 2.5

1.87 ± 1.8

3.8 ± 2.5*

2.0 ± 1.8

2.5 ± 2.7

1.9 ± 1.8

3.2 ± 2.4*

GOLD classification

        

GOLD 1-2

46 (58)

12 (57)

53 (61)

5 (38)

48 (61)

10 (48)

49 (60)

9 (47)

GOLD 3-4

33 (42)

9 (43)

34 (39)

8 (62)

31 (39)

11 (52)

32 (40)

10 (53)

Hospitalizations previous year

0.3 ± 0.7

1.0 ± 1.8*

0.25 ± 0.6

1.6 ± 2.1Ŧ

0.3 ± 0.6

1.0 ± 1.8

0.2 ± 0.5

1.5 ± 1.9Ŧ

ED visits previous year

1.0 ± 1.6

0 ± 1.7

1.0 ± 1.5

2.2 ± 3.2

1.2 ± 1.9

1.2 ± 1.9

1.0 ± 1.5

1.9 ± 2.8

Psychological variables

        

HADS anxiety

3.3 ± 3.2

5.9 ± 5.9

3.8 ± 3.9

4.1 ± 5.3

4.0 ± 3.9

3.3 ± 4.5

4.0 ± 4.1

3.3 ± 4.1

HADS depression

3.6 ± 3.5

5.5 ± 47

3.9 ± 3.7

4.5 ± 4.8

4.0 ± 3.9

3.8 ± 3.9

3.9 ± 3.7

4.3 ± 4.4

  1. Data are presented as mean ± standard deviation (X ± SD), unless otherwise indicated.
  2. BMI body mass index, MRC scale Medical Research Council dyspnea scale, FVC post forced vital capacity post-bronchodilatation, FEV1 post forced expiratory volumen in 1-s post-bronchodilatation, 6MWT 6-min walking test, BODE index Body mass index, Degree of Airflow Obstruction, Dyspnea and Exercise Capacity Index; GOLD Global Initiative for Chronic Obstructive Lung Disease.
  3. P values: comparisons between groups were tested using the Pearson´s X2or Fisher´s Exact test (categorical variables) or ANOVA (normally distributed continuous variables) and Mann–Whitney U test (non-normally distributed variables or non-parametric data).
  4. ** p < .1 *p < .05; †p < .01; Ŧp < .001.