Patient-reported outcomes in adequately treated hypothyroidism – insights from the German versions of ThyDQoL, ThySRQ and ThyTSQ

Table 2 Spearman correlations between the ThyDQoL, ThyTSQ, and ThySRQ items

ThyDQoL indices	ThyDQoL AWI-18	ThyDQoL AWI-14	ThyDQoL Present QoL	ThyDQoL Impact on QoL	ThyTSQ sumscore
AWI-18	-----	0.97*	0.51*	0.75*	0.57*
AWI-14	-----	-----	0.52*	0.72*	0.56*
Present QoL	-----	-----	-----	0.30*	0.48*
Impact on QoL	-----	-----	-----	-----	0.55*
ThySRQ symptom bother ratings
Tiredness	-0.39**	-0.39**	-0.28**	-0.34**	-0.37**
Weight gain	-0.38**	-0.33**	-0.14 n.s.	-0.34**	-0.27*
Cold	-0.23*	-0.20 n.s.	-0.27*	-0.14 n.s.	-0.07 n.s.
Constipation	-0.13 n.s.	-0.09 n.s.	-0.08 n.s.	-0.18 n.s.	-0.16 n.s.
Hair	-0.29*	-0.32**	-0.27*	-0.24*	-0.26*
Skin	-0.35**	-0.35**	-0.26*	-0.31**	-0.26*
Nails	-0.31**	-0.31**	-0.23*	-0.34**	-0.21 n.s.
Appetite	-0.25*	-0.23*	-0.19 n.s.	-0.11 n.s.	-0.02 n.s.
Hearing	-0.14 n.s.	-0.12 n.s.	-0.08 n.s.	-0.13 n.s.	0.03 n.s.
Voice	-0.32**	-0.30*	-0.30**	-0.05 n.s.	-0.21*
Speech	-0.37**	-0.35**	-0.22*	-0.25*	-0.13 n.s.
Memory	-0.22*	-0.20 n.s.	-0.22*	-0.20 n.s.	-0.06 n.s.
Concentration	-0.42**	-0.43**	-0.47**	-0.26*	-0.43**
Giddy	-0.33**	-0.32**	-0.23*	-0.31**	-0.22*
Depressed	-0.48**	-0.46**	-0.56**	-0.27*	-0.45**

*p < 0.05, **p < 0.0033 corrected for multiple testing within ThySRQ symptom bother ratings. Abbreviations: ThyDQoL – Thyroid-Dependent Quality of Life Questionnaire, ThySRQ – Underactive Thyroid Symptom Rating Questionnaire, ThyTSQ – Thyroid Treatment Satisfaction Questionnaire, AWI – Average Weighted Impact Score, QoL – Quality of Life.

ISSN: 1477-7525