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Table 3 Changes in HRQOL health-utility scores and clinical anchors between pre-treatment and follow-up

From: Minimal clinically important differences for the EQ-5D and QWB-SA in Post-traumatic Stress Disorder (PTSD): results from a Doubly Randomized Preference Trial (DRPT)

Measures N Mean (SD) Effect size
CGI-S 155 -2.6 (1.5) 2.06
CGI-I* 155 1.7 (1.1) N/A
PSS-I 155 17.9 (10.8) 2.03
Treatment Response† 155 130 (83.9%) N/A
EQ-5D 155 0.15 (0.22) 0.77
QWB-SA 155 0.09 (0.15) 0.64
  1. HRQOL, Health-Related Quality of Life; SD, Standard Deviation; CGI-I, Clinical Global Impression-Improvement; CGI-S, Clinical Global Impression-Severity; PTSD, Post-traumatic Stress Disorder; PSS-I, PTSD Symptom Scale-Interview; EQ-5D, EuroQol Group-5 Dimensions; QWB-SA, Quality of Well-Being-Self Administration.
  2. * Note that CGI-I was only given at post-treatment and thereafter.
  3. † Treatment response was measured as number (n) and percent (%) of patients who responded to treatment.