Minimal clinically important differences for the EQ-5D and QWB-SA in Post-traumatic Stress Disorder (PTSD): results from a Doubly Randomized Preference Trial (DRPT)

Table 3 Changes in HRQOL health-utility scores and clinical anchors between pre-treatment and follow-up

Measures	N	Mean (SD)	Effect size
CGI-S	155	-2.6 (1.5)	2.06
CGI-I*	155	1.7 (1.1)	N/A
PSS-I	155	17.9 (10.8)	2.03
Treatment Response†	155	130 (83.9%)	N/A
EQ-5D	155	0.15 (0.22)	0.77
QWB-SA	155	0.09 (0.15)	0.64

HRQOL, Health-Related Quality of Life; SD, Standard Deviation; CGI-I, Clinical Global Impression-Improvement; CGI-S, Clinical Global Impression-Severity; PTSD, Post-traumatic Stress Disorder; PSS-I, PTSD Symptom Scale-Interview; EQ-5D, EuroQol Group-5 Dimensions; QWB-SA, Quality of Well-Being-Self Administration.
* Note that CGI-I was only given at post-treatment and thereafter.
† Treatment response was measured as number (n) and percent (%) of patients who responded to treatment.

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