Health-related quality of life and life satisfaction in colorectal cancer survivors: trajectories of adjustment

Table 3 Predictors of CL trajectory class for various FACT-C sub domains (N = 1618)

Predictor	Adjusted OR (95% CI) for constant low (CL) class relative to constant high (CH) class
Predictor	Physical	Social/Family	Emotional wellbeing	Functional	Colorectal cancer specific
Sex (Male)		3.52* (1.9, 6.4)		0.39* (0.2, 0.8)	0.23* (0.1, 0.4)
Age (Younger^a)		1.48* (1.1, 2.1)	1.89* (1.3, 2.7)
Socioeconomic Disadv.					1.37* (1.1, 1.8)
Disease stage
Stages 0, I, II	Reference		Reference	Reference
Stages III, IV	2.61* (1.7, 3.9)		2.20* (1.2, 3.9)	2.97* (1.5, 5.9)
Unknown
Remoteness of residence
Major city					0.42* (0.2, 0.9)
Inner regional					Reference
Outer regional
Remote/very remote
Social support (Dissatified^b)		7.83* (3.7, 16)	1.29* (1.0, 1.6)	1.95* (1.3, 2.9)	1.51* (1.2, 2.0)
Low cancer threat appraisal	1.09* (1.0, 1.2)	1.19* (1.1, 1.3)	1.29* (1.1, 1.5)	1.79* (1.5, 2.1)	1.37* (1.2, 1.5)
Low optimism	1.06* (1.0, 1.1)	1.26* (1.2, 1.4)	1.22* (1.1, 1.3)	1.26* (1.1, 1.5)	1.14* (1.1, 1.2)

* shown only significant results at 0.05 level on the adjusted log odds of being in the CL class versus the CH class.
^a patient age is categorized into “20-49”, “50-59”, “60-69”, “70-80” (treated as ordinal in GMMs).
^b satisfaction with social support received (ordinal scale from 0 “very dissatisfied” to 5 “very satisfied”).

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