Health-related quality of life and life satisfaction in colorectal cancer survivors: trajectories of adjustment

Table 2 Predictors of FACT-C trajectory class membership (N = 1618)

Predictor	Adjusted OR (95% CI) relative to constant high (CH) class			p-value ^c
Predictor	Constant medium	Medium decrease	Constant low	p-value ^c
Sex (Male)	0.76 (0.5, 1.1)	1.55 (0.7, 3.6)	0.48* (0.3, 0.9)	0.024
Age (Younger^a)	0.99 (0.8, 1.3)	1.22 (0.8, 1.9)	1.74* (1.3, 2.4)	< 0.001
Disease stage				0.002
Stages 0, I, II	Reference	Reference	Reference
Stages III, IV	1.26 (0.8, 2.0)	3.46* (1.7, 7.1)	2.13* (1.1, 4.2)
Unknown	0.74 (0.4, 1.4)	1.21 (0.4, 3.4)	0.69 (0.3, 1.6)
Social support (Dissatified^b)	1.42* (1.0, 2.0)	1.14 (0.7, 1.9)	2.32* (1.6, 3.3)	< 0.001
Low cancer threat appraisal	1.27* (1.2, 1.4)	1.24* (1.1, 1.4)	1.77* (1.6, 2.0)	< 0.001
Low optimism	1.10* (1.0, 1.2)	1.06 (1.0, 1.1)	1.27* (1.2, 1.4)	< 0.001

* significant at 0.05 level on the adjusted log odds of being in the class versus the Constant High class.
^a patient age is categorized into “20-49”, “50-59”, “60-69”, “70-80” (treated as ordinal in GMMs).
^b satisfaction with social support received (ordinal scale from 0 “very dissatisfied” to 5 “very satisfied”).
^c likelihood ratio test (full model versus model without the predictor under consideration).

ISSN: 1477-7525