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Table 4 Psychometric properties at optimal cut-off values for generalized anxiety disorder and any anxiety disorder screening in patients with negative depression screening results

From: Screening for anxiety disorders in patients with coronary artery disease

Cut-off score

N (%)

Sensitivity,% (95% CI)

Specificity,% (95% CI)

PPV,% (95% CI)

NPV,% (95% CI)

HADS-D score <5, n = 340

Generalized anxiety disorder

HADS-A ≥ 8

49 (14)

89 (51–99)

88 (83–91)

16 (8–10)

100 (98–100)

STAI ≥ 45

104 (31)

89 (51–99)

71 (66–76)

8 (4–15)

100 (97–100)

SSAI ≥ 40

118 (35)

89 (51–99)

67 (61–72)

7 (3–13)

100 (97–100)

Any anxiety disorder

HADS-A ≥ 8

49 (14)

69 (41–88)

88 (84–91)

22 (12–37)

98 (96–99)

STAI ≥ 45

104 (31)

87 (58–98)

72 (67–77)

13 (71–21)

99 (97–100)

SSAI ≥ 40

118 (35)

81 (54–95)

68 (62–73)

11 (6–18)

99 (96–100)

BDI-II score <14, n = 370

Generalized anxiety disorder

HADS-A ≥ 8

45 (12)

80 (30–99)

89 (85–92)

9 (3–22)

100 (98–100)

STAI ≥ 45

110 (30)

60 (17–93)

71 (66–75)

3 (1–8)

99 (97–100)

SSAI ≥ 40

126 (34)

60 (17–93)

66 (61–71)

2 (1–7)

99 (97–100)

Any anxiety disorder

HADS-A ≥ 8

45 (12)

50 (20–80)

89 (85–92)

11 (4–25)

98 (96–99)

STAI ≥ 45

110 (30)

70 (35–92)

71 (66–76)

6 (3–13)

99 (96–100)

SSAI ≥ 40

126 (34)

50 (20–80)

66 (61–71)

4 (1–9)

98 (95–99)

  1. BDI-II – Beck Depression Inventory-II; CI – confidence interval; HADS -A – Hospital Anxiety and Depression scale – Anxiety subscale; HADS -D – Hospital Anxiety and Depression scale – Depression subscale NPV- negative predictive value; PPV - positive predictive value.