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Table 4 Psychometric properties at optimal cut-off values for generalized anxiety disorder and any anxiety disorder screening in patients with negative depression screening results

From: Screening for anxiety disorders in patients with coronary artery disease

Cut-off score N (%) Sensitivity,% (95% CI) Specificity,% (95% CI) PPV,% (95% CI) NPV,% (95% CI)
HADS-D score <5, n = 340
Generalized anxiety disorder
HADS-A ≥ 8 49 (14) 89 (51–99) 88 (83–91) 16 (8–10) 100 (98–100)
STAI ≥ 45 104 (31) 89 (51–99) 71 (66–76) 8 (4–15) 100 (97–100)
SSAI ≥ 40 118 (35) 89 (51–99) 67 (61–72) 7 (3–13) 100 (97–100)
Any anxiety disorder
HADS-A ≥ 8 49 (14) 69 (41–88) 88 (84–91) 22 (12–37) 98 (96–99)
STAI ≥ 45 104 (31) 87 (58–98) 72 (67–77) 13 (71–21) 99 (97–100)
SSAI ≥ 40 118 (35) 81 (54–95) 68 (62–73) 11 (6–18) 99 (96–100)
BDI-II score <14, n = 370
Generalized anxiety disorder
HADS-A ≥ 8 45 (12) 80 (30–99) 89 (85–92) 9 (3–22) 100 (98–100)
STAI ≥ 45 110 (30) 60 (17–93) 71 (66–75) 3 (1–8) 99 (97–100)
SSAI ≥ 40 126 (34) 60 (17–93) 66 (61–71) 2 (1–7) 99 (97–100)
Any anxiety disorder
HADS-A ≥ 8 45 (12) 50 (20–80) 89 (85–92) 11 (4–25) 98 (96–99)
STAI ≥ 45 110 (30) 70 (35–92) 71 (66–76) 6 (3–13) 99 (96–100)
SSAI ≥ 40 126 (34) 50 (20–80) 66 (61–71) 4 (1–9) 98 (95–99)
  1. BDI-II – Beck Depression Inventory-II; CI – confidence interval; HADS -A – Hospital Anxiety and Depression scale – Anxiety subscale; HADS -D – Hospital Anxiety and Depression scale – Depression subscale NPV- negative predictive value; PPV - positive predictive value.