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Table 1 Demographic, clinical, serological and capillaroscopic data of the eSSc and UCTD patients

From: Quality of life as measured by the short-form 36 (SF-36) questionnaire in patients with early systemic sclerosis and undifferentiated connective tissue disease

Feature

Early SSc

UCTD

P

 

n = 31

n = 35

 

Sex: F/M (n)

29/2

34/1

ns

Age; years (median; range)

41 (17–64)

40 (18–73)

ns

RaP duration; years (median; range)

3 (1–24)

4 (0.5-30)

ns

Puffy fingers (n;%)

3 (9.6)

0 (0)

ns

History of arthritis (n;%)

0 (0)

4 (11.4)

0.052

ESR >20 mm/h (n;%)

5 (16.1)

3 (8.5)

ns

Gammaglobulins > 1.5 g/dl (n;%)

2 (6.4)

2 (5.7)

ns

C3 < 80 mg/dl or C4 < 15 mg/dl (n;%)

2 (6.4)

3 (8.5)

ns

DLCO < 80% of predicted (n;%)

7 (22.5)

5/20 (25.0)*

ns

E/A ratio < 1** (n;%)

2 (6.4)

1 (2.8)

ns

ANA + (n;%)

30 (96.7)

35 (100)

ns

SSc-marker antibodies + (n;%)

27 (87.0)

0 (0)

-

ACA + (n;%)

20 (64.5)

0 (0)

-

Anti-Scl-70 + (n;%)

6 (19.3)

0 (0)

-

ESSG-AI > 3 (n;%)

0 (0)

-

-

NCM SSc pattern (n;%)

22 (70.9)

0 (0)

-

Calcium channel blockers (n;%)

31 (100)

35 (100)

ns

  1. * In 20 out of 35 UCTD patients the DLCO was measured; **Not otherwise explained.
  2. All data are expressed as numbers and percentages (in brackets), except were otherwise indicated.
  3. SSc = systemic sclerosis; UCTD = undifferentiated connective tissue disease; n = number; F = female; M = male; ns = not statistically significant; RaP = Raynaud’s phenomenon; DLCO = carbon monoxide lung diffusion; E/A ratio <1, inverted ratio between early (E)/late (atrial = A) ventricular filling velocity; ESR = erythrocyte sedimentation rate; ANA = antinuclear antibodies; ACA = anticentromere antibodies; ESSG-AI = European Scleroderma study group activity index; NCM = nailfold capillary microscopy.