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Table 4 Partial correlations between IBS-QOL total score and other clinical measures—controlling for dose level

From: Evaluation of the Irritable Bowel Syndrome Quality of Life (IBS-QOL) questionnaire in diarrheal-predominant irritable bowel syndrome patients

Variable Time point N Correlation type Correlation value p-Value
IBS-SSS Week 12 427 Pearson -0.604 <0.0001
  Change from Baseline 383 Pearson -0.629 <0.0001
EQ-5D Week 12 694 Pearson 0.581 <0.0001
  Change from Baseline 690 Pearson 0.404 <0.0001
Pain/14-Day Week 12 550 Pearson -0.392 <0.0001
  Change from Baseline 549 Pearson -0.350 <0.0001
Pain/7-Day Week 12 536 Pearson -0.397 <0.0001
  Change from Baseline 535 Pearson -0.357 <0.0001
IBS-AR Week 12 693 Point Biserial 0.379 <0.0001
(t-Test) (10.788)
Biserial 0.483 <0.0001
(t-Test) (14.523)
FDA clinical responder definition Week 12 694 Point Biserial 0.282 <0.0001
(t-Test) (7.750)
Biserial 0.395 <0.0001
(t-Test) (11.316)
  1. Note: Point biserial and biserial correlation coefficients are evaluated via constructing a t-test.