Health and Quality of Life Outcomes

Table 4 Regression of the EQ-5D and SF-6D utility indices upon FACT-G

From: Mapping the FACT-G cancer-specific quality of life instrument to the EQ-5D and SF-6D

	OLS model			GLM model			CLAD model
	1	2	3*	1	2	3*	1	2	3*
EQ-5D
FACT-G	0.006^§			0.008^§			0.005^§
PWB		0.009^§	0.010^§		0.012^§	0.013^§		0.006^§	0.012^§
FWB		0.008^§	0.006^‡		0.010^§	0.007^‡		0.007^§	0.005^§
EWB		0.005^†	0.006^†		0.006^†	0.008^†		0.005^‡	0.002^§
Colorectal¹			0.018			0.019			0.012
Lung			-0.022			-0.023			0.019
Stage-2²			-0.018			-0.021			-0.030
Stage-3			0.019			0.025			0.016
Stage-4			0.026			0.034			-0.009
Constant	0.345	0.391	0.267	-0.798	-0.746	-0.867	0.380	0.481	0.281
Adjusted R²	0.331	0.396	0.469
LL	125.736	136.033	144.088	125.924	136.068	143.054
RMSE	0.120	0.113	0.104	0.120	0.113	0.111	0.122	0.116	0.095
MAE	0.090	0.086	0.077	0.089	0.085	0.077	0.924	0.086	0.078
N	180	180	162	180	180	162	180	180	164
SF-6D
FACT-G	0.005^§			0.008^§			0.005^§
PWB		0.011^§	0.011^§		0.016^§	0.0159^§		0.009^§	0.012^§
FWB		0.007^§	0.007^§		0.011^§	0.0096^§		0.008^§	0.007^§
EWB		0.001	0.002		0.001	0.003		0.005^‡	-0.004^§
Colorectal¹			0.006			0.002			-0.027
Lung			-0.009			-0.016			-0.050
Stage-2²			-0.015			-0.023			-0.031
Stage-3			0.028			0.039			0.016
Stage-4			-0.006			-0.005			-0.022
Constant	0.278	0.343	0.281	-0.982	-0.895	-0.956	0.331	0.282	0.438
Adj_R^2	0.508	0.628	0.651
LL	207.344	233.806	222.229	209.645	237.754	224.711
RMSE	0.077	0.066	0.062	0.076	0.065	0.061	0.077	0.069	0.076
MAE	0.062	0.056	0.051	0.061	0.054	0.050	0.062	0.056	0.057
N	182	182	164	182	182	164	182	181	166

*Model 3 -adjusted for age and sex Reference group – ¹Breast Cancer; ²Cancer Stage 1; ^†p < 0.05, ^‡p < 0.01, ^§p < 0.001; LL = Log-likelihood; MAE = Mean Absolute Error; RMSE = Root Mean Square Error. FACT-G: Functional Assessment of Cancer Therapy; PWB: Physical well-being; FWB: Functional well-being; EWB: Social well-being; EWB: Emotional well-being.

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