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Table 6 Significant HRQoL predictors of HU from stepwise regression model with adjustment for baseline patient characteristics

From: Use of health-related quality of life measures to predict health utility in postmenopausal osteoporotic women: results from the Multiple Outcomes of Raloxifene Evaluation study

Non-EU cohort EU cohort
Dependent Var = HUI; Independent Vars = OPAQ, NHP, BD Dependent Var = EQ-5D; Independent Vars = QualEFFO, NHP, BD
Domain C Domain C
OPAQ Walking/Bending 0.137*** QualEFFO pain 0.108**
OPAQ fear of falls 0.071** QualEFFO daily activity 0.644***
OPAQ fatigue 0.057* QualEFFO mental health 0.141*
NHP emotional reaction −0.096*** NHP emotional reaction −0.299***
NHP pain −0.169*** NHP pain −0.154***
NHP sleep −0.056***   
NHP social interaction −0.109*   
Variance explained 0.48 Variance explained 0.64
  1. Abbreviations: BD Baseline demographic (characteristic), C Regression coefficient EU, European Union, HUI Health Utility Index, NHP Nottingham Health Profile, Non-EU Non-European Union, OPAQ Osteoporosis Assessment Questionnaire, QualEFFO EU Foundation of Osteoporosis Quality-of-Life Assessment, Var variable.
  2. Scoring: OPAQ scores: 0 (worst) - 100 (best), HUI scores: 0 (worst) - 1.0 (best), NHP scores: 0 (best) - 100 (worst), EQ-5D scores: 0 (worst) - 1.0 (best), QualEFFO scores (54-item QualEFFO): 0 (worst) - 100 (best).
  3. *p < 0.05, **p < 0.001, ***p < 0.0001.