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Table 6 Significant HRQoL predictors of HU from stepwise regression model with adjustment for baseline patient characteristics

From: Use of health-related quality of life measures to predict health utility in postmenopausal osteoporotic women: results from the Multiple Outcomes of Raloxifene Evaluation study

Non-EU cohort

EU cohort

Dependent Var = HUI; Independent Vars = OPAQ, NHP, BD

Dependent Var = EQ-5D; Independent Vars = QualEFFO, NHP, BD

Domain

C

Domain

C

OPAQ Walking/Bending

0.137***

QualEFFO pain

0.108**

OPAQ fear of falls

0.071**

QualEFFO daily activity

0.644***

OPAQ fatigue

0.057*

QualEFFO mental health

0.141*

NHP emotional reaction

−0.096***

NHP emotional reaction

−0.299***

NHP pain

−0.169***

NHP pain

−0.154***

NHP sleep

−0.056***

  

NHP social interaction

−0.109*

  

Variance explained

0.48

Variance explained

0.64

  1. Abbreviations: BD Baseline demographic (characteristic), C Regression coefficient EU, European Union, HUI Health Utility Index, NHP Nottingham Health Profile, Non-EU Non-European Union, OPAQ Osteoporosis Assessment Questionnaire, QualEFFO EU Foundation of Osteoporosis Quality-of-Life Assessment, Var variable.
  2. Scoring: OPAQ scores: 0 (worst) - 100 (best), HUI scores: 0 (worst) - 1.0 (best), NHP scores: 0 (best) - 100 (worst), EQ-5D scores: 0 (worst) - 1.0 (best), QualEFFO scores (54-item QualEFFO): 0 (worst) - 100 (best).
  3. *p < 0.05, **p < 0.001, ***p < 0.0001.