Multivariate structural equation model predicting the associations of CML treatment restrictions, treatment doses, NME, CML treatment satisfaction, and patient-reported outcomes among CML patients. Note. The following covariates or non-significant predictors (of adherence, activity impairment, MCS, PCS, and health utilities) are not presented: age, gender, number of comorbidities, time since diagnosis, and number of non-CML medications taken per day. Straight lines indicate betas and curved lines indicate correlations. Residual error terms, estimated for all predicted variables and factors, are not presented; neither are correlation estimates. Non-parenthetical values are standardized estimates (ranging from −1 to +1, with 0 = no effect) indicating strength and direction of association; these values can be compared across predictors. P-values are based on the unstandardized path estimates. No p-values are available for the first indicators per factor, which set the scale. Fit statistics indicate a fair fit of the data to the model (χ2 test of model fit=408.8; df=76; p-value<0.01. CFI=0.79; TLI=0.63; RMSEA=0.12). CML = chronic myeloid leukemia, NME = negative medication experience.