Health-related quality of life and survival in Chinese patients with chronic liver disease

Table 2 HRQOL and clinical data of different groups (mean ± SE)

Items	Healthy control	Chronic liver disease		ANOVA
	Healthy control	Surviving patients	Deceased patients
	n = 86	n = 365	n = 50
Physical function	93.2 ± 6.4	86.6 ± 15.4	70.1 ± 29.9	P < 0.001
Physical roles	88.8 ± 15.6	80.5 ± 19.3	63.0 ± 32.6	P < 0.001
Bodily pain	85.1 ± 15.1	87.3 ± 14.2	72.9 ± 26.2	P < 0.001
General health	75.3 ± 18.1	56.3 ± 21.3	44.9 ± 28.7	P < 0.001
Vitality	83.5 ± 12.0	76.1 ± 10.7	42.7 ± 21.9	P < 0.001
Social roles	94.1 ± 10.6	81.0 ± 20.0	39.5 ± 21.0	P < 0.001
Emotional roles	92.9 ± 10.7	89.6 ± 13.4	54.4 ± 26.3	P < 0.001
Mental health	87.9 ± 25.0	79.3 ± 11.0	52.2 ± 23.4	P < 0.001
PCS	54.1 ± 5.2	48.9 ± 7.7	33.5 ± 8.2	P < 0.001
MCS	56.6 ± 8.2	53.0 ± 5.6	37.1 ± 12.1	P < 0.001
Laboratory data
Albumin (g/L)	37.0 ± 2.7	35.3 ± 7.4	24.5 ± 4.8	P < 0.001
ALT (U/L)	23.0 ± 10.4	56.3 ± 62.8	37.8 ± 31.7	P = 0.001
AST (U/L)	23.4 ± 12.7	63.3 ± 69.5	82.7 ± 69.4	P < 0.001
GGT (U/L)	51.8 ± 58.0	102.8 ± 146.3	123.9 ± 216.9	P = 0.088
ALP (U/L)	105.6 ± 72.0	126.8 ± 94.9	140.7 ± 128.0	P = 0.267
TBIL (umol/L)	9.4 ± 3.9	26.8 ± 35.7	81.4 ± 77.1	P < 0.001
BUN (umol/L)	5.0 ± 0.9	5.4 ± 2.8	9.9 ± 7.4	P < 0.001
Cr (umol/L)	68.8 ± 14.7	77.2 ± 26.0	109.1 ± 65.5	P < 0.001
Prothrombin time (s)	10.5 ± 0.5	13.3 ± 2.8	18.3 ± 5.7	P < 0.001
WBC (10⁹/L)	6.0 ± 1.4	4.7 ± 2.0	5.6 ± 4.7	P < 0.001
Hemoglobin (g/L)	136.0 ± 19.8	118.7 ± 25.4	90.6 ± 20.7	P < 0.001
Platelet (10⁹/L)	210.4 ± 35.0	131.1 ± 75.3	77.3 ± 44.5	P < 0.001
K (mmol/L)	4.0 ± 0.3	4.0 ± 0.4	3.8 ± 0.7	P = 0.041
Na (mmol/L)	140.2 ± 3.5	140.8 ± 7.9	135.7 ± 6.9	P < 0.001

PCS physical component summary, MCS mental component summary, ALT alanine aminotransferase, AST aspartate aminotransferase, ALP alkaline phosphatase, GGT γ-glutamyl transferase, TBIL total bilirubin, Cr serum creatine, BUN blood urea nitrogen, K serum potassium, Na serum sodium, WBC white blood cell.

ISSN: 1477-7525