Validation of the controlled ovarian stimulation impact measure (COSI): assessing the patient perspective

Table 3 Factor-analysis of core COSI items using a 4 factor solution and Varimax rotation ^†

Variable	Factor				Communality
Variable	1	2	3	4
	Psychological health	Compliance worry	Interference in daily life	Injection burden
Feel stressed	77			21	0.68
Feel emotional ups and downs	73				0.59
Feel emotionally exhausted	73		23		0.61
Feel anxious	66			21	0.51
Feel depressed	63		21		0.46
Feel strain or tension in relationship	54				0.32
Feel not able to manage life	49		30		0.35
Feel good about self*	47				0.29
Feel physically exhausted	47				0.26
Bothered: side effects from the med.	46				0.25
Worry: taking the correct dose		84			0.75
Worry: injecting properly		80		28	0.73
Worry: missing a dose		66	21		0.50
Worry: medication at the right time	27	64	21		0.54
Problem: learn how to take properly		45	30	27	0.38
Problem: manage or schedule time	25	21	85		0.84
Problem: keep up family/soc. life	35		62		0.53
Problem: travel or short trips			58		0.38
Convenient take meds at corr. time*			40		0.21
Problem: schedule monitoring visits		24	39		0.25
Bothered: injections	22		21	89	0.91
Bothered: injections required	29			76	0.72
Bothered: having to inject myself		28		60	0.45
Bothered: problems injection site	32		21	43	0.34

† Excluding work-related questions, including imputed missing values.
* Variables have been mirrored for the analysis. Factor loadings have been multiplied by 100.
Factor loadings with an (absolute) value <0.2 were not printed.
The communality indicates the proportion of variance explained by the 4 factor solution.
COSI Controlled ovarian stimulation impact measure.

ISSN: 1477-7525