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Table 2 Responsiveness of MusiQoL and SF-36 in the 107 worsened patients

From: Responsiveness of the Multiple Sclerosis International Quality of Life questionnaire to disability change: a longitudinal study

 

Baseline

Month 6

Month 12

Month 18

Month 24

MusiQoL

M (SD)

M (SD)

D M6-BL

ES

M (SD)

D M12-BL

ES

M (SD)

D M18-BL

ES

M (SD)

D M24-BL

ES

ADL

50.0 (24.4)

46.9 (25.2)

−3.33

−0.14

49.4 (26.1)

−1.04

−0.04

47.1 (26.9)

−3.04

−0.12

46.8 (28.2)

−3.53

−0.14

PWB

62.6 (22.1)

62.5 (23.0)

−0.56

−0.02

64.8 (22.5)

2.04

0.09

61.7 (23.2)

−1.33

−0.06

64.3 (23.9)

1.67

0.08

SPT

64.7 (21.3)

68.1 (21.6)

3.54*

0.16

69.2 (20.4)

4.29**

0.20

65.3 (21.6)

0.22

0.07

67.2 (21.3)

2.16

0.10

RFr

62.2 (25.0)

59.3 (24.6)

−2.72

−0.11

60.3 (24.0)

−1.33

−0.05

64.4 (23.4)

1.55

0.06

60.3 (23.6)

−1.67

−0.07

RFa

74.6 (22.5)

73.2 (21.9)

−1.35

−0.06

69.7 (25.3)

−4.46

−0.20

73.4 (23.0)

−1.83

−0.08

72.6 (23.2)

−2.17

−0.10

SSL

63.3 (29.4)

59.5 (28.7)

−3.65

−0.12

57.7 (29.3)

−4.89*

−0.16

54.3 (30.5)

−9.62***

−0.32

56.1 (30.6)

−6.38*

−0.21

COP

66.1 (27.0)

66.7 (26.1)

0.36

0.01

67.2 (26.1)

0.12

0.00

67.3 (27.2)

1.14

0.04

64.5 (28.6)

−0.73

−0.03

REJ

78.7 (27.7)

78.1 (24.4)

−0.36

−0.01

79.4 (23.8)

0.61

0.02

78.1 (24.8)

−0.38

−0.01

78.2 (24.8)

−0.12

−0.00

RHCS

86.8 (14.8)

82.6 (19.1)

−4.49**

−0.30

82.9 (17.2)

−3.96**

−0. 27

81.9 (20.4)

−4.93**

−0. 33

80.7 (19.7)

−5.98***

−0 .40

Index

67.0 (13.1)

65.8 (13.9)

−1.12

−0.09

66.1 (13.1)

−1.08

−0.08

65.7 (13.8)

−2.46**

−0.19

65.2 (15.0)

−2.26

−0.17

SF-36v2

M (SD)

M (SD)

D M6-BL

ES

M (SD)

D M12-BL

ES

M (SD)

D M18-BL

ES

M (SD)

D M24-BL

ES

PF

48.4 (28.5)

45.2 (29.0)

−2.95

−0.10

46.6 (29.8)

−2.19

−0.08

42.9 (30.4)

−5.37**

−0.19

41.1 (32.0)

−7.84***

−0. 28

RP

50.4 (27.9)

50.3 (28.8)

−0.04

−0.00

50.9 (28.1)

−0.55

−0.02

45.1 (27.8)

−4.60

−0.17

46.0 (29.8)

−4.83*

−0.17

BP

67.6 (26.3)

64.1 (26.7)

−3.88

−0.15

64.1 (25.7)

−3.10

−0.12

61.6 (28.2)

−5.88**

−0. 22

60.9 (27.3)

−7.44***

−0. 28

GH

49.5 (21.2)

50.2 (18.8)

0.89

0.04

47.4 (20.1)

−2.83

−0.13

49.3 (20.0)

−0.59

−0.03

47.9 (21.4)

−2.27

−0.11

Vi

43.5 (18.3)

45.7 (20.2)

2.08

0.11

44.6 (19.6)

1.04

0.06

43.1 (19.4)

−0.58

−0.03

44.1 (20.3)

0.58

0.03

SF

65.8 (24.1)

64.9 (25.5)

−1.09

−0.04

65.3 (27.4)

−0.25

−0.01

65.0 (25.5)

−0.98

−0.04

61.9 (28.7)

−3.85

−0.16

RE

53.0 (14.9)

54.8 (12.5)

1.29

−0.09

52.5 (13.3)

−0.59

−0.04

52.8 (13.7)

−0.80

−0.05

51.7 (14.4)

−1.94

−0.13

MH

65.4 (18.7)

66.8 (18.0)

0.98

0.05

64.6 (20.5)

−1.04

−0.06

64.3 (18.2)

−1.85

−0.10

63.2 (20.4)

−3.12

−0.17

PCS

39.6 (9.9)

38.1 (9.8)

−1.19

−0.12

38.9 (9.5)

−0.93

−0.09

37.4 (10.6)

−2.13**

−0. 22

37.3 (11.1)

−2.59***

−0. 26

MCS

44.9 (8.6)

46.2 (8.5)

1.30

0.15

45.1 (8.6)

0.50

0.06

45.1 (8.1)

0.16

0.02

45.1 (8.9)

−0.11

−0.01

  1. MusiQoL Multiple Sclerosis Quality of Life questionnaire.
  2. ADL activity of daily living, PWB psychological well-being, SPT symptoms, RFr relationships with friends, RFa relationships with family, SSL sentimental and sexual life, COP coping, REJ rejection, RHCS relationships with health care system.
  3. SF-36v2 Short Form 36 version 2.
  4. PF physical functioning, RP role physical, BP bodily pain, GH general health, Vi vitality, SF social functioning, RE role-emotional, MH mental health, PCS physical component summary, MCS mental component summary.
  5. M (SD), mean (standard deviation).
  6. DMi-BL: difference mean between the score of the evaluation time and the baseline score (a positive difference indicates a QoL improvement and a negative difference indicates a QoL deterioration), *p < =0.05, **p < =0.01, ***p < =0.001.
  7. ES, effect size; bold values indicate effect sizes > = 0.20.
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Health and Quality of Life Outcomes

ISSN: 1477-7525

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