Health-related quality of life in family members of patients with an advanced cancer diagnosis: A one-year prospective study

Sjolander, Catarina; Rolander, Bo; Järhult, Johannes; Mårtensson, Jan; Ahlstrom, Gerd

doi:10.1186/1477-7525-10-89

Table 3 HRQOL scores by age groups (n = 18 each) at 3 to 15 months (n = 36)

	A1 Md	A1 M [SE]	p-value	A2 Md	A2 M [SE]	p-value	A3 Md	A3 M [SE]	p-value	A4 Md	A4 M [SE]	p-value	A5 Md	A5 M [SE]	p-value
PCS
20-65 years	55	52 [±2.3]	0.006**	56	55 [±2.7]	0.003**	50	50 [±2.1]	0.025*	52	50 [±2.7]	0.005**	54	52 [±2.7]	0.011*
66-84 years	40	41 [±2.5]		45	44 [±2.5]		42	42 [±2.6]		41	39 [±2.6]		45	42 [±2.4]
MCS
20-65 years	35	33 [±2.8]	0.007**	37	35 [±4.3]	0.036	36	35 [±4.0]	0.147	44	40 [±3.0]	0.117	40	36 [±3.9]	0.078
66-84 years	47	45 [±2.9]		47	47 [±2.3]		41	42 [±2.7]		49	46 [±3.0]		47	45 [±2.7]
PF
20-65 years	100	89 [±5.1]	<0.001***	100	94 [±2.7]	<0.001***	95	86 [±4.4]	0.012*	100	91 [±3.3]	0.001**	95	91 [±3.6]	0.006**
66-84 years	69	70 [±4.2]		75	74 [±4.9]		73	72 [±4.4]		75	69 [±4.7]		78	72 [±5.4]
RP
20-65 years	100	79 [±6.8]	0.021*	100	87 [±8.0]	0.107	100	68 [±10.3]	0.321	100	72 [±10.2]	0.174	75	71 [±10.2]	0.458
66-84 years	50	49 [±9.5]		75	67 [±9.2]		75	53 [±11.2]		50	53 [±10.0]		100	61 [±10.0]
BP
20-65 years	61	65 [±7.0]	0.649	72	71 [±7.1]	0.699	51	63 [±7.8]	0.440	57	66 [±6.8]	0.651	73	69 [±7.0]	0.271
66-84 years	41	60 [±6.8]		62	66 [±6.4]		51	57 [±6.3]		52	59 [±5.4]		57	60 [±4.9]
GH
20-65 years	62	62 [±4.8]	0.622	67	70 [±4.0]	0.303	77	68 [±5.2]	0.232	65	65 [±4.9]	0.070	70	70 [±5.1]	0.283
66-84 years	57	58 [±4.8]		67	61 [±4,8]		57	57 [±4.4]		62	57 [±4.0]		65	61 [±4.9]
VT
20-65 years	40	42 [±4.2]	0.013	55	51 [±6.2]	0.221	48	50 [±6.7]	0.726	55	54 [±5.0]	0.645	53	50 [±6.3]	0.341
66-84 years	65	58 [±4.2]		60	61 [±5.2]		50	54 [±4.4]		60	56 [±6.2]		60	59 [±4.2]
SF
20-65 years	75	68 [±6.4]	0.141	75	73 [±7.5]	0.262	83	64 [±7.0]	0.478	88	75 [±6.4]	0.646	75	72 [±6.6]	0.265
66-84 years	88	79 [±5.6]		100	83 [±5.3]		69	71 [±5.3]		75	78 [±5.6]		93	81 [±5.7]
RE
20-65 years	67	57 [±11.0]	0.878	100	60 [±11.8]	0.208	67	56 [±12.1]	0.694	100	76 [±8.5]	0.986	67	52 [±12.2]	0.286
66-84 years	67	59 [±10.1]		100	76 [±8.0]		83	63 [±10.0]		100	74 [±8.7]		100	68 [±9.5]
MH
20-65 years	50	53 [±4.0]	0.006	52	57 [±5.8]	0.061	56	57 [±6.4]	0.240	60	58 [±5.4]	0.193	62	60 [±6.1]	0.436
66-84 years	72	70 [±4.8]		76	71 [±5.4]		64	67 [±3.8]		76	68 [±4.9]		70	67 [±4.5]
EQ-5D Index
20-65 years	0.82	0.74 [±0.05]	0.591	0.73	0.73 [±0.05]	0.652	0.76	0.75 [±0.06]	0.392	0.80	0.80 [±0.05]	0.403	0.80	0.71 [±0.06]	0.254
66-84 years	0.73	0.72 [±0.05]		0.80	0.80 [±0.05]		0.73	0.71 [±0.04]		0.78	0.78 [±0.05]		0.76	0.70 [±0.06]
EQ-5D VAS
20-65 years	70	74 [±5.3]	0.774	70	70 [±4.6]	0.373	75	67 [±6.6]	0.973	75	73 [±4.3]	0.679	60	62 [±5.7]	0.115
66-84 years	75	72 [±3.5]		80	80 [±3.5]		75	72 [±3.0]		75	70 [±4.2]		80	75 [±3.3]

Independent Samples Mann–Whitney U Test * p < 0.05, ** p < 0.01, *** p < 0.001, ns = not significant.
A1 = 3 months, A2 = 6 months, A3 = 9 months, A4 = 12 months, A5 = 15 months.
PCS = Physical Component Summary Score, MCS = Mental Component Summary Score, PF = Physical Functioning, RP = Role Physical, BP = Bodily Pain, GH = General Health, VT = Vitality, SF = Social Functioning, RE = Role Emotional, MH = Mental Health, EQ-5D Index = EQ-5D index score, EQ-5D VAS = EQ-5D visual analog scale.

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ISSN: 1477-7525

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