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Table 3 HRQOL scores by age groups (n = 18 each) at 3 to 15 months (n = 36)

From: Health-related quality of life in family members of patients with an advanced cancer diagnosis: A one-year prospective study

  A1 Md A1 M [SE] p-value A2 Md A2 M [SE] p-value A3 Md A3 M [SE] p-value A4 Md A4 M [SE] p-value A5 Md A5 M [SE] p-value
PCS                
20-65 years 55 52 [±2.3] 0.006** 56 55 [±2.7] 0.003** 50 50 [±2.1] 0.025* 52 50 [±2.7] 0.005** 54 52 [±2.7] 0.011*
66-84 years 40 41 [±2.5]   45 44 [±2.5]   42 42 [±2.6]   41 39 [±2.6]   45 42 [±2.4]  
MCS                
20-65 years 35 33 [±2.8] 0.007** 37 35 [±4.3] 0.036 36 35 [±4.0] 0.147 44 40 [±3.0] 0.117 40 36 [±3.9] 0.078
66-84 years 47 45 [±2.9]   47 47 [±2.3]   41 42 [±2.7]   49 46 [±3.0]   47 45 [±2.7]  
PF                
20-65 years 100 89 [±5.1] <0.001*** 100 94 [±2.7] <0.001*** 95 86 [±4.4] 0.012* 100 91 [±3.3] 0.001** 95 91 [±3.6] 0.006**
66-84 years 69 70 [±4.2]   75 74 [±4.9]   73 72 [±4.4]   75 69 [±4.7]   78 72 [±5.4]  
RP                
20-65 years 100 79 [±6.8] 0.021* 100 87 [±8.0] 0.107 100 68 [±10.3] 0.321 100 72 [±10.2] 0.174 75 71 [±10.2] 0.458
66-84 years 50 49 [±9.5]   75 67 [±9.2]   75 53 [±11.2]   50 53 [±10.0]   100 61 [±10.0]  
BP                
20-65 years 61 65 [±7.0] 0.649 72 71 [±7.1] 0.699 51 63 [±7.8] 0.440 57 66 [±6.8] 0.651 73 69 [±7.0] 0.271
66-84 years 41 60 [±6.8]   62 66 [±6.4]   51 57 [±6.3]   52 59 [±5.4]   57 60 [±4.9]  
GH                
20-65 years 62 62 [±4.8] 0.622 67 70 [±4.0] 0.303 77 68 [±5.2] 0.232 65 65 [±4.9] 0.070 70 70 [±5.1] 0.283
66-84 years 57 58 [±4.8]   67 61 [±4,8]   57 57 [±4.4]   62 57 [±4.0]   65 61 [±4.9]  
VT                
20-65 years 40 42 [±4.2] 0.013 55 51 [±6.2] 0.221 48 50 [±6.7] 0.726 55 54 [±5.0] 0.645 53 50 [±6.3] 0.341
66-84 years 65 58 [±4.2]   60 61 [±5.2]   50 54 [±4.4]   60 56 [±6.2]   60 59 [±4.2]  
SF                
20-65 years 75 68 [±6.4] 0.141 75 73 [±7.5] 0.262 83 64 [±7.0] 0.478 88 75 [±6.4] 0.646 75 72 [±6.6] 0.265
66-84 years 88 79 [±5.6]   100 83 [±5.3]   69 71 [±5.3]   75 78 [±5.6]   93 81 [±5.7]  
RE                
20-65 years 67 57 [±11.0] 0.878 100 60 [±11.8] 0.208 67 56 [±12.1] 0.694 100 76 [±8.5] 0.986 67 52 [±12.2] 0.286
66-84 years 67 59 [±10.1]   100 76 [±8.0]   83 63 [±10.0]   100 74 [±8.7]   100 68 [±9.5]  
MH                
20-65 years 50 53 [±4.0] 0.006 52 57 [±5.8] 0.061 56 57 [±6.4] 0.240 60 58 [±5.4] 0.193 62 60 [±6.1] 0.436
66-84 years 72 70 [±4.8]   76 71 [±5.4]   64 67 [±3.8]   76 68 [±4.9]   70 67 [±4.5]  
EQ-5D Index                
20-65 years 0.82 0.74 [±0.05] 0.591 0.73 0.73 [±0.05] 0.652 0.76 0.75 [±0.06] 0.392 0.80 0.80 [±0.05] 0.403 0.80 0.71 [±0.06] 0.254
66-84 years 0.73 0.72 [±0.05]   0.80 0.80 [±0.05]   0.73 0.71 [±0.04]   0.78 0.78 [±0.05]   0.76 0.70 [±0.06]  
EQ-5D VAS                
20-65 years 70 74 [±5.3] 0.774 70 70 [±4.6] 0.373 75 67 [±6.6] 0.973 75 73 [±4.3] 0.679 60 62 [±5.7] 0.115
66-84 years 75 72 [±3.5]   80 80 [±3.5]   75 72 [±3.0]   75 70 [±4.2]   80 75 [±3.3]  
  1. Independent Samples Mann–Whitney U Test * p < 0.05, ** p < 0.01, *** p < 0.001, ns = not significant.
  2. A1 = 3 months, A2 = 6 months, A3 = 9 months, A4 = 12 months, A5 = 15 months.
  3. PCS = Physical Component Summary Score, MCS = Mental Component Summary Score, PF = Physical Functioning, RP = Role Physical, BP = Bodily Pain, GH = General Health, VT = Vitality, SF = Social Functioning, RE = Role Emotional, MH = Mental Health, EQ-5D Index = EQ-5D index score, EQ-5D VAS = EQ-5D visual analog scale.