Health-related quality of life in family members of patients with an advanced cancer diagnosis: A one-year prospective study

Table 2 HRQOL scores of family members at five assessments compared to norm-based scores (n = 36)

	Norm-based score □ # M [SE]	A1 Md	A1 M [SE]	A2 Md	A2 M [SE]	A2-A1 p-value	A3 Md	A3 M [SE]	A3-A1 p-value	A4 Md	A4 M [SE]	A4-A1 p-value	A5 Md	A5 M [SE]	A5-A1 p-value
PCS	□44.6 [±1.02]	45	46 [±1.9]	52	49 [±2.0]*	0.33	48	46 [±1.8]	0.96	48	45 [±2.0]	0.66	51	47 [±2.0]	0.66
MCS	□51.1 [±0.97]	38	39 [±2.2]*	44	42 [±2.5]*	0.53	38	39 [±2.4]*	0.91	45	43 [±2.2]*	0.25	45	41 [±2.4]*	0.71
PF	□78.2 [±1.94]	83	79 [±3.6]	90	83 [±3.2]	0.42	89	80 [±3.2]	0.77	85	80 [±3.4]	0.85	90	81 [±3.6]	0.69
RP	□70.1[±3.42]	75	63 [±6.4]	100	74 [±6.4]	0.22	88	60 [±7.7]	0.77	75	62 [±7.2]	0.89	88	66 [±7.1]	0.76
BP	□66.0 [±2.35]	56	63 [±4.8]	62	67 [±4.4]	0.55	52	63 [±4.2]	0.95	51	60 [±4.9]	0.67	62	64 [±4.2]	0.82
GH	□67.2 [±2.04]	59	60 [±3.4]	67	64 [±3.1]	0.33	65	62 [±3.1]	0.65	67	62 [±3.5]	0.63	67	65 [±3.6]	0.28
VT	□67.3 [±2.09]	48	50 [±3.3]*	58	57 [±3.9] *	0.19	50	54 [±3.9]*	0.47	58	55 [±4.0]*	0.39	58	55 [±3.7]*	0.36
SF	□88.3 [±1.73]	75	74 [±4.3]*	94	79 [±4.2] *	0.45	69	70 [±4.3]*	0.46	81	77 [±4.2]*	0.68	88	77 [±4.3]*	0.68
RE	□81.6 [±2.86]	67	58 [±7.3]*	100	69 [±6.7] *	0.30	83	60 [±7.7]*	0.88	100	75 [±6.0]	0.08	84	61 [±7.6]*	0.82
MH	□80.5 [±1.68]	64	62 [±3.4]*	66	65 [±4.0] *	0.58	60	63 [±3.6] *	0.79	68	63 [±3.7]*	0.83	66	64 [±3.7]*	0.70
EQ5D Index	#0.8 [±0.01]	0.80	0.73 [±0.04]	0.76	0.75 [±0.03]	0.91	0.73	0.73 [±0.04]	0.50	0.80	0.72 [±0.04]	0.71	0.80	0.70 [±0.04]*	0.35
EQ-5D VAS	#79.7 [±0.83]	75	73 [±3.0]*	79	74 [±2.8]*	0.76	75	70 [±3.4]**	0.98	75	71[±3.0]**	0.91	70	69 [±3.3]**	0.61

A1 = 3 months, A2 = 6 months, A3 = 9 months, A4 = 12 months, A5 = 15 months.
Data at A2–A5 were compared with data at A1 (linear mixed models for repeated observations).
□ Norm-based score = Norms for the general Swedish population (age group 60–64 years), Sullivan et al. 2002. # Norm-based score = UK population norms for the EQ-5D (age group 55–64 years), Kind et al. 1999.
PCS = Physical Component Summary Score, MCS = Mental Component Summary Score, PF = Physical Functioning, RP = Role Physical, BP = Bodily Pain, GH = General Health, VT = Vitality, SF = Social Functioning, RE = Role Emotional, MH = Mental Health, EQ-5D Index = EQ-5D index score, EQ-5D VAS = EQ-5D visual analog scale.
* p < 0.05, ** p < 0.01 = Statistically significant differences between norm-based scores and mean scores in the present study at A1–A5.

ISSN: 1477-7525