Table 3 HRQoL dimensions in different stages of Chronic Kidney Disease (CKD) and in healthy controls
HRQoL- dimensions | Controls vs CKD 2–3# | Controls (n = 55) Md (IQR)CI | CKD 2–3* (n = 54) GFR range 31–69 Mean (SD),CI | CKD 4* (n = 87) GFR range 15–29 Mean (SD),CI | CKD 5* (n = 394) GFR range 2–14 Mean (SD),CI | CKD 2–3 vs CKD 4–5## |
|---|---|---|---|---|---|---|
Physical | Z = −3.53 | 100 | 83.7 (22) | 57 (28.5) | 49.2 (28.7) | F = 67.1 |
functioning | p = .000 | (95–100) | 77.7–89.7 | 50.9–63 | 46.3–52 | p = .000 |
(PF) | 94.2–99 | |||||
Role | Z = −3.08 | 100 | 69 (37.3) | 39.9 (45) | 22.1 (35.6) | F = 64.3 |
physical | p = .002 | (100–100) | 58.8–79.2 | 30.4–49.5 | 15.5–25.6 | p = .000 |
(RP) | 78.5–95.1 | |||||
Bodily | Z = −2.51 | 84 | 71.5 (27.2) | 63.8 (30.3) | 58.8 (31.4) | F = 7.1 |
Pain | p = .012 | (74–100) | 64.1–79 | 57.3–70.2 | 55.7–61.9 | p = .008 |
(BP) | 80.9–89.4 | |||||
General | Z = −5.63 | 85 | 59.4 (21.5) | 40.8 (17.8) | 40.2 (18.9) | F = 49.3 |
health | p = .000 | (77–95) | 53.5–65.3 | 37–44.6 | 38.3–42.1 | p = .000 |
(GH) | 78.9–86.8 | |||||
Vitality, | Z = −2.29 | 75 | 61.5 (25.1) | 48.3 (26.1) | 36.5 (23.9) | F = 41.3 |
energy | p = .022 | (65–85) | 54.6–68.3 | 42.8–53.9 | 34.2–38.9 | p = .000 |
(VT) | 68.2–77.8 | |||||
Social | Z = −2.39 | 100 | 83.3 (22.5) | 67 (28.4) | 57 (30.7) | F = 33 |
functioning | p = .017 | (88–100) | 77.2–89.5 | 60.9–73 | 53.9–60 | p = .000 |
(SF) | 90.3–96.9 | |||||
Role | Z = −2.59 | 100 | 79 (35.6) | 62.1 (43.5) | 38.8 (42.5) | F = 34.3 |
emotional | p = .009 | (100–100) | 69.3–88.7 | 52.8–71.3 | 34.6–43 | p = .000 |
(RE) | 86.6–98.9 | |||||
Mental | Z = −2.39 | 84 | 75.9 (18.2) | 71.6 (18.7) | 62.9 (23.1) | F = 13 |
health | p = .017 | (80–92) | 71–80.9 | 67.7–75.6 | 60.6–65.1 | p = .000 |
(MH) | 81.8–87.6 | |||||
Physical | Z = −4.35 | 55 | 45.8 (10.4) | 34.9 (11.9) | 32.9 (10.5) | F = 66.6 |
Composite | p = .000 | (52.4–57.3) | 43–48.6 | 32.4–37.4 | 31.9–33.9 | p = .000 |
summary | 51.4–55.1 | |||||
(PCS) | ||||||
Mental | Z = −1.92 | 53 | 47.4 (10.6) | 45 (12.4) | 38.5 (12.8) | F = 17.9 |
composite | p = .055 | (48.6–56) | 44.5–50.3 | 42.4–47.6 | 37.2–39.7 | p = .000 |
summary | 49.3–53.5 | |||||
(MCS) |