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Table 3 HRQoL dimensions in different stages of Chronic Kidney Disease (CKD) and in healthy controls

From: Health-related quality of life in different stages of chronic kidney disease and at initiation of dialysis treatment

HRQoL- dimensions Controls vs CKD 2–3# Controls (n = 55) Md (IQR)CI CKD 2–3* (n = 54) GFR range 31–69 Mean (SD),CI CKD 4* (n = 87) GFR range 15–29 Mean (SD),CI CKD 5* (n = 394) GFR range 2–14 Mean (SD),CI CKD 2–3 vs CKD 4–5##
Physical Z = −3.53 100 83.7 (22) 57 (28.5) 49.2 (28.7) F = 67.1
functioning p = .000 (95–100) 77.7–89.7 50.9–63 46.3–52 p = .000
(PF)   94.2–99     
Role Z = −3.08 100 69 (37.3) 39.9 (45) 22.1 (35.6) F = 64.3
physical p = .002 (100–100) 58.8–79.2 30.4–49.5 15.5–25.6 p = .000
(RP)   78.5–95.1     
Bodily Z = −2.51 84 71.5 (27.2) 63.8 (30.3) 58.8 (31.4) F = 7.1
Pain p = .012 (74–100) 64.1–79 57.3–70.2 55.7–61.9 p = .008
(BP)   80.9–89.4     
General Z = −5.63 85 59.4 (21.5) 40.8 (17.8) 40.2 (18.9) F = 49.3
health p = .000 (77–95) 53.5–65.3 37–44.6 38.3–42.1 p = .000
(GH)   78.9–86.8     
Vitality, Z = −2.29 75 61.5 (25.1) 48.3 (26.1) 36.5 (23.9) F = 41.3
energy p = .022 (65–85) 54.6–68.3 42.8–53.9 34.2–38.9 p = .000
(VT)   68.2–77.8     
Social Z = −2.39 100 83.3 (22.5) 67 (28.4) 57 (30.7) F = 33
functioning p = .017 (88–100) 77.2–89.5 60.9–73 53.9–60 p = .000
(SF)   90.3–96.9     
Role Z = −2.59 100 79 (35.6) 62.1 (43.5) 38.8 (42.5) F = 34.3
emotional p = .009 (100–100) 69.3–88.7 52.8–71.3 34.6–43 p = .000
(RE)   86.6–98.9     
Mental Z = −2.39 84 75.9 (18.2) 71.6 (18.7) 62.9 (23.1) F = 13
health p = .017 (80–92) 71–80.9 67.7–75.6 60.6–65.1 p = .000
(MH)   81.8–87.6     
Physical Z = −4.35 55 45.8 (10.4) 34.9 (11.9) 32.9 (10.5) F = 66.6
Composite p = .000 (52.4–57.3) 43–48.6 32.4–37.4 31.9–33.9 p = .000
summary   51.4–55.1     
(PCS)       
Mental Z = −1.92 53 47.4 (10.6) 45 (12.4) 38.5 (12.8) F = 17.9
composite p = .055 (48.6–56) 44.5–50.3 42.4–47.6 37.2–39.7 p = .000
summary   49.3–53.5     
(MCS)       
  1. * CKD-stage according to Table 1 . GFR = glomerular filtration rate in ml/min/1.73 m².
  2. # Post hoc Mann–Whitney U -Test.## ANOVA One-way Test df = 533.
  3. Confidence interval at 95% interval