Validation of the Danish version of the disease specific instrument EORTC QLQ-CR38 to assess Health-related quality of life in patients with colorectal cancer

Table 4 Known-groups comparison for the relevant scales

Scales (Item number)	Age		Gender		Physical performance		Type cancer		Stoma		Type surgery		Physical status
	<64 years vs. >64 years	P- value	Male vs. female	P-value	Excellent or good vs. less good or bad	P-value	Colon vs. rectum	P-value	No stoma vs. stoma	P-value	Open vs. laparoskopic	P-value	ASA 1 vs. ASA 2-3	P-value
	n = 77/87		n = 104/60		n = 81/57		n = 87/21		n = 110/53		n = 101/61		n = 55/99
Micturition problems (31–33)	26 vs. 23	0.17	28 vs. 18	0.001			23 vs. 24	0.96
Symptoms gastro- intestinal tract (34–38)							20 vs. 18	0.14			22 vs. 14	0.007
Weight loss (39)	13 vs. 21	0.07					26 vs. 19	0.46			29 vs. 26	0.9
Chemotherapy side effects (40–42)
Body image (43–45)					84 vs. 75	0.02			84 vs. 73	0.001	78 vs. 83	0.07
Future Perspective (46)	55 vs. 60	0.45			65 vs. 50	0.001							57 vs. 58	0.88
Sexual functioning (47–48)	29 vs. 12	0.001	25 vs. 12	0.000					22 vs. 17	0.07	19 vs. 24	0.12	16 vs. 29	0.001
Sexual enjoyment (49)
Male sexual problems (50–51)	28 vs. 52	0.008							27 vs. 63	0.001	50 vs. 23	0.002	29 vs. 44	0.12
Female sexual problems (52–53)
Defecation problems (55–61)	20 vs. 12	0.009	18 vs. 13	0.2			14 vs. 24	0.004
Stoma-related problems (62–68)

Mean score and P-value for between-groups differences.
Bolding indicates between-groups differences ≥ 5 points and a P-value < 0.05 (Mann-Witney U-tests).