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Table 3 Predictors of Beliefs in Medicines Questionnaire (BMQ) scale responses a

From: Beliefs about chelation among thalassemia patients

 

Slope (SE)

p-value

Predictors of Specific Necessity - DFO

  

Monotherapy vs. combination therapy

2.39 (0.75)

0.002

Regularly transfused

2.84 (1.02)

0.006

Number of complications

0.39 (0.18)

0.031

Predictors of Specific Concerns - DFO

  

Age group

 

0.04

  Young adult vs. child

−2.45 (0.95)

 

  Adult vs. child

−1.87 (0.99)

 

Race

 

<0.001

  Asian vs. white

1.91 (0.66)

 

  Other vs. white

−5.25 (2.15)

 

Country

 

0.004

  Canada vs. US

1.89 (0.93)

 

  UK vs. US

2.80 (1.03)

 

Predictors of Specific Necessity – Oral Chelator

  

Monotherapy vs. combination therapy

3.47 (0.66)

<0.001

Parent vs. self

1.06 (0.53)

0.048

Race

 

<0.001

  Asian vs. white

−0.19 (0.46)

 

  Other vs. white

−3.74 (1.01)

 

Country

 

0.002

  Canada vs. US

0.31 (0.68)

 

  UK vs. US

2.49 (0.72)

 

Predictors of Specific Concerns - Oral Chelator

  

Parent vs. self

2.61 (0.77)

0.001

Age group

 

0.005

  Young adult vs. child

1.42 (0.80)

 

  Adult vs. child

2.39 (0.74)

 

Race

 

<0.001

  Asian vs. white

1.63 (0.49)

 

  Other vs. white

2.94 (1.01)

 

Female vs. male

−1.19 (0.46)

0.01

Predictors of General Overuse

  

Race

 

0.006

  Asian vs. white

0.26 (0.30)

 

  Other vs. white

2.01 (0.62)

 

Country

 

0.05

  Canada vs. US

0.90 (0.37)

 

  UK vs. US

0.48 (0.48)

 

Predictors of General Harm

  

Age group

 

0.04

  Young adult vs. child

−0.20 (0.40)

 

  Adult vs. child

−0.91 (0.37)

 

Race

 

0.02

  Asian vs. white

0.19 (0.31)

 

  Other vs. white

1.76 (0.64)

 

Country

 

0.007

  Canada vs. US

0.03 (0.39)

 

  UK vs. US

1.64 (0.52)

 

Predictors of General Benefit

  

Parent vs. self

0.62 (0.27)

0.02

Race

 

0.03

  Asian vs. white

0.08 (0.25)

 

  Other vs. white

−1.33 (0.53)

 

Predictors of Sensitive Soma

  

Number of complications

0.29 (0.12)

0.02

  1. a Multivariate analysis of covariance model with backwards elimination. Predictors: respondent (parent vs. self), age group (child 5–17, young adult 18–24, adult 25+), gender, race (White, Asian, other), country (US, Canada, UK), diagnosis (β vs. E-β thal), regularly transfused (at least 8 transfusions in the past year), and number of complications (congestive heart failure, ventricular arrhythmia, low cardiac T2* by MRI, type I or II diabetes, growth hormone deficiency, hypothyroidism, hypoparathyroidism, hypogonadotropic hypogonadism, cirrhosis, alloimmunization, active hepatitis C, chronic active hepatitis B, and HIV).