Figure 2

Mean overall activity impairment by flare frequency and presence of tophi, after adjusting for age, gender, and length of illness. Higher values indicate greater impairment; error bars represent standard error of the mean. Those with any flares are significantly more impaired than those without flares after adjusting for age, gender, and length of illness. Compared with those without tophi, those unsure of tophi were also more impaired (p < 0.05) and there was a trend for greater impairment among those with tophi (p = 0.07).