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Table 4 Adjusted mean Sleep Disturbance scores by baseline severity of heartburn symptoms

From: Health-related quality of life improves with treatment-related GERD symptom resolution after adjusting for baseline severity

Trial/Follow-up   N Mean (s.e.)
Clinical Trial 1    
8 Weeks None/Minor 59 75.0 (2.3)
  Mild 158 73.9 (1.5)
  Moderate 58 77.3 (2.4)
  Severe 13 74.3 (5.1)
Clinical Trial 3    
4 Weeks None/Minor 39 75.7 (3.8)
  Mild 20 69.2 (5.1)
  Moderate 72 72.4 (2.7)
  Severe 79 66.4 (2.6)
12 Weeks None/Minor 36 75.0 (3.8) *
  Mild 16 70.8 (5.6)
  Moderate 66 71.3 (2.9)
  Severe 65 62.8 (2.9)
24 Weeks None/Minor 33 75.6 (4.3)
  Mild 14 73.3 (6.4)
  Moderate 63 70.0 (3.1)
  Severe 69 66.3 (3.0)
  1. *p < 0.05 for test of overall differences in least square means from ANCOVA model, adjusted for gender, age, relevant baseline sleep disturbance score, and symptom resolution status.