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Table 3 Adjusted mean PGWB total scores by baseline severity of heartburn symptoms

From: Health-related quality of life improves with treatment-related GERD symptom resolution after adjusting for baseline severity

Trial/Follow-up   n Mean (s.e.)
Clinical Trial 1    
8 Weeks None/Minor 59 80.5 (1.6)
  Mild 159 80.3 (1.0)
  Moderate 59 82.0 (1.6)
  Severe 13 87.5 (3.5)
Clinical Trial 2    
4 Weeks None/Minor 237 82.4 (0.8)
  Mild 219 81.8 (0.9)
  Moderate 160 82.5 (1.0)
  Severe 33 82.3 (2.2)
8 Weeks None/Minor 234 83.4 (0.9)
  Mild 219 82.1 (0.9)
  Moderate 155 83.7 (1.1)
  Severe 35 82.3 (2.3)
12 Weeks None/Minor 231 84.4 (0.9)
  Mild 217 83.1 (1.0)
  Moderate 151 85.8 (1.2)
  Severe 34 82.5 (2.4)
16 Weeks None/Minor 229 86.0 (0.9)
  Mild 211 84.8 (1.0)
  Moderate 153 88.4 (1.2)
  Severe 32 86.8 (2.5)
Clinical Trial 3    
4 Weeks None/Minor 40 76.0 (3.0)
  Mild 21 73.7 (3.9)
  Moderate 79 72.8 (2.0)
  Severe 84 70.9 (2.0)
12 Weeks None/Minor 37 76.9 (3.2) *
  Mild 17 71.9 (4.5)
  Moderate 71 74.0 (2.3)
  Severe 69 64.3 (2.4)
24 Weeks None/Minor 37 74.5 (3.5)
  Mild 18 69.6 (4.8)
  Moderate 68 72.4 (2.5)
  Severe 74 67.4 (2.4)
  1. *p < 0.05 for test of overall differences in least square means from ANCOVA model, adjusted for gender, age, relevant baseline PGWB total score, and symptom resolution status.