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Table 2 Baseline HRQL by baseline measure of heartburn severity

From: Health-related quality of life improves with treatment-related GERD symptom resolution after adjusting for baseline severity

Baseline level of heartburn severity Clinical Trial 1 Clinical Trial 2 Clinical Trial 3
  n1 PGWB Total, mean (s.e.) MOS Sleep, mean (s.e.) n1 PGWB Total, mean (s.e.) MOS Sleep, mean (s.e.) n PGWB Total, mean (s.e.) MOS Sleep, mean (s.e.)
None/Minor 65 81.0 (1.9) * 74.1 (3.0) * 250 74.5 (1.1) * NA 43 71.4 (3.1) * 64.1 (4.4) *
Mild 166 77.8 (1.2) 70.3 (1.9) 232 74.9 (1.2) NA 21 63.0 (4.5) 60.8 (6.4)
Moderate 63 71.0 (2.0) 61.3 (3.1) 165 69.6 (1.4) NA 90 58.8 (2.2) 58.0 (3.1)
Severe 13 60.1 (4.3) 36.4 (6.7) 36 66.6 (3.0) NA 97 50.1 (2.1) 48.2 (2.9)
  1. 1Due to missing data points Ns may not sum to total trial sample size. *p < 0.05 for test of overall differences in means from one-way ANCOVA model.