STUDY A | STUDY B | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Mean Change Score (N) | Mean Change Score (N) | |||||||||
Outcome Measure | <50% | ≥50% and <75% | ≥75% | F statistic | p value | < 50% | ≥50% and <75% | ≥75% | F statistic | p value |
PSA Frequency (8 items) | 2.38 (232) | 6.48 (97) | 8.75 (110) | 61.71 | <0.0001 | 2.35 (269) | 7.16 (149) | 9.71 (125) | 85.65 | <0.0001 |
PSA Frequency (7 items) | 1.90 (232) | 5.15 (97) | 7.12 (111) | 49.81 | <0.0001 | 1.90 (269) | 5.94 (149) | 7.98 (125) | 72.61 | <0.0001 |
PSA Severity (8 items) | 2.45 (231) | 7.05 (97) | 9.93 (111) | 69.06 | <0.0001 | 2.52 (271) | 7.87 (149) | 10.52 (125) | 88.46 | <0.0001 |
PSA Severity (7 items) | 1.95 (231) | 5.76 (97) | 8.19 (111) | 58.82 | <0.0001 | 2.05 (271) | 6.47 (149) | 8.79 (125) | 77.04 | <0.0001 |
PSA TOTAL Scale (16 items) | 4.79 (230) | 13.53 (96) | 18.63 (110) | 69.76 | <0.0001 | 4.88 (269) | 15.03 (149) | 20.23 (125) | 91.77 | <0.0001 |
DLQI TOTAL | 2.48 (223) | 5.33 (97) | 9.57 (104) | 54.61 | <0.0001 | 2.49 (268) | 6.83 (146) | 10.03 (122) | 75.05 | <0.0001 |
DLQI Symptom and Feelings | 0.74 (235) | 1.70 (98) | 2.94 (110) | 69.64 | <0.0001 | 0.79 (271) | 2.14 (150) | 2.95 (127) | 94.27 | <0.0001 |
DLQI Daily Activities | 0.45 (234) | 1.13 (98) | 2.14 (110) | 41.11 | <0.0001 | 0.61 (270) | 1.47 (150) | 2.17 (127) | 42.37 | <0.0001 |
DLQI Leisure | 0.40 (235) | 0.96 (98) | 1.81 (111) | 27.70 | <0.0001 | 0.60 (271) | 1.08 (150) | 1.89 (126) | 22.34 | <0.0001 |
DLQI Work and School | 0.28 (226) | 0.46 (97) | 0.62 (106) | 5.41a | <0.0001 | 0.17 (269) | 0.52 (147) | 0.73 (123) | 16.44b | <0.0001 |
DLQI Personal Relationships | 0.20 (236) | 0.45 (98) | 1.20 (111) | 17.89 | <0.0001 | 0.12 (271) | 0.75 (150) | 1.21 (126) | 25.21 | <0.0001 |
DLQI Treatment | 0.22 (236) | 0.65 (98) | 1.05 (111) | 24.90 | <0.0001 | 0.14 (271) | 0.81 (149) | 1.08 (126) | 41.70b | <0.0001 |
NPF Itch Scale | n/a | n/a | n/a | n/a | n/a | 0.59 (273) | 1.65 (150) | 2.34 (127) | 58.13 | <0.0001 |
VAS Itch Scale | 0.79 (235) | 2.97 (98) | 4.34 (111) | 56.96 | <0.0001 | n/a | n/a | n/a | n/a | n/a |