| | | | |
COPD
| |
|---|
| |
Healthy (ex)smokers
|
At Risk (Stage 0)
|
Mild (Stage I)
|
Moderate (Stage IIA)
|
Moderate (Stage IIB)
|
Severe (Stage III)
|
|
N
|
44
|
18
|
15
|
20
|
16
|
6
|
|
Males (%)
|
48
|
33
|
60
|
70
|
81
|
100
|
|
Age, yr
|
51 (45–71)
|
53 (42–61)
|
54 (48–66)
|
57 (46–73)
|
66 (49–74)
|
59 (53–69)
|
|
Pack yr
|
24 (4–66)
|
29 (2–67)
|
31 (20–77)
|
35 (15–77)
|
36 (10–85)
|
34 (12–45)
|
|
Current smoking(%)
|
89
|
100
|
100
|
85
|
75
|
83
|
|
FEV1 (%pred)
|
101 (62–128)
|
105 (82–132)
|
93 (81–116)
|
69 (51–75)
|
41 (30–49)
|
24 (22–28)
|
- Healthy (ex) smokers; normal spirometry, no chronic symptoms (cough, sputum production). COPD classification of COPD by severity according to the GOLD guidelines; Stage 0: normal spirometry, chronic symptoms (cough, sputum production); Stage I: FEV1/FVC < 70%, FEV1 ≥ 80 % predicted, with or without chronic symptoms (cough, sputum production, dyspnea); Stage IIA: FEV1/FVC < 70%, 50% ≥ FEV1 < 80 % predicted; Stage IIB: FEV1/FVC < 70%, 30% ≥ FEV1 < 50 % predicted; Stage III: FEV1/FVC < 70%, FEV1 < 30 % predicted or FEV1 < 50% predicted plus respiratory failure or clinical signs of right heart failure.